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Now showing items 41-45 of 45
The "Goldilocks Zone" from a redox perspective-Adaptive vs. deleterious responses to oxidative stress in striated muscle
(2014-09-18)
Consequences of oxidative stress may be beneficial or detrimental in physiological systems. An organ system's position on the “hormetic curve” is governed by the source and temporality of reactive oxygen species (ROS) ...
Comparison of Whole Blood and Peripheral Blood Mononuclear Cell Gene Expression for Evaluation of the Perioperative Inflammatory Response in Patients with Advanced Heart Failure
(2014-12-17)
Background: Heart failure (HF) prevalence is increasing in the United States.
Mechanical Circulatory Support (MCS) therapy is an option for Advanced HF
(AdHF) patients. Perioperatively, multiorgan dysfunction (MOD) is ...
Cytotoxic and Pathogenic Properties of Klebsiella oxytoca Isolated from Laboratory Animals
(2014-07)
Klebsiella oxytoca is an opportunistic pathogen implicated in various clinical diseases in animals and humans. Studies suggest that in humans K. oxytoca exerts its pathogenicity in part through a cytotoxin. However, cytotoxin ...
Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells
(2014)
Hepatocellular carcinoma (HCC) is characterized by limited response to current
drug therapies. Here, we report that SC66, a novel AKT inhibitor, reduced cell viability
in a dose- and time-dependent manner, inhibited ...
Introduction: Biology and the Idea of Culture
(2014)
This chapter analyses Frankenstein's dramatization of the costs and consequences of the drive for transcendence in terms of humanist culture's anxieties about human and nonhuman identities in capitalist production. The ...