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A systematic mRNA control mechanism for germline stem cell homeostasis and cell fate specification
(2016-02)
Germline stem cells (GSCs) are the best understood adult stem cell types in the nematode Caenorhabditis elegans, and have provided an important model system for studying stem cells and their cell fate in vivo, in mammals. ...
A simple and rapid method for combining fluorescent in situ RNA hybridization (FISH) and immunofluorescence in the C. elegans germline
(2016-05-06)
Imaging of RNAs and proteins in specific tissues has opened ample avenues to understand gene expression during development. Recently, a fluorescent in situ RNA hybridization (FISH) method has been developed to analyze the ...
Development of a RAD-Seq Based DNA Polymorphism Identification Software, AgroMarker Finder, and Its Application in Rice Marker-Assisted Breeding
(2016-01-22)
Rapid and accurate genome-wide marker detection is essential to the marker-assisted breeding and functional genomics studies. In this work, we developed an integrated soft- ware, AgroMarker Finder (AMF: http://erp.novelb ...
Design of a prospective, multicenter, global, cohort study of electromagnetic navigation bronchoscopy
(2016-04-26)
Background: Electromagnetic navigation bronchoscopy (ENB) procedures allow physicians to access peripheral lung lesions beyond the reach of conventional bronchoscopy. However, published research is primarily limited to ...
Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA)
(2016-08)
The International Agency for Research on Cancer (IARC) Monographs Programme identifies chemicals, drugs, mixtures, occupational exposures, lifestyles and per- sonal habits, and physical and biological agents that cause ...
Conclusions: Ontological Relations and the Spatial Politics of Capital Cities
(2016-01)
The frontispiece to this this volume, an example of an urban beautification mural project with a view of the alborz Mountains in southern tehran, visualizes the
focus of this book on political landscapes of capital cit- ...
Development of a new diabetes medication self-efficacy scale and its association with both reported problems in using diabetes medications and self-reported adherence
(2016-06-07)
Background: Although there are several different general diabetes self-efficacy scales, there is a need to develop a self-efficacy scale that providers can use to assess patient’s self-efficacy regarding medication use. ...
Computational Modeling of PI3K/AKT and MAPK Signaling Pathways in Melanoma Cancer
(2016-03-25)
Background
Malignant melanoma is an aggressive tumor of the skin and seems to be resistant to current therapeutic approaches. Melanocytic transformation is thought to occur by sequential accu- mulation of genetic and ...
Commentary: Effect of Skeletal Muscle Native Tropomyosin on the Interaction of Amoeba Actin with Heavy Meromyosin
(2016-08-31)
Keywords: troponin, tropomyosin, cardiomyopathy, troponin T, mutations
Troponin-tropomyosin inhibits skeletal and cardiac muscle contraction at low Ca
rigor-type myosin S1 to actin-tropomyosin-troponin, particularly at ...
Acid ceramidase is upregulated in AML and represents a novel therapeutic target
(2016-12-13)
There is an urgent unmet need for new therapeutics in acute myeloid leukemia (AML) as standard therapy has not changed in the past three decades and outcome remains poor for most patients. Sphingolipid dysregulation through ...