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Position Paper From the Association of Pathology Chairs: Surgical Pathology Residency Training
(2018-12-10)
Training in surgical pathology specimen dissection and microscopic diagnosis is an integral part of pathology residency training, as surgical pathology is one of the defining activities of most pathologists. The Accreditation ...
Glaucomatous optic disc changes despite normal baseline intraocular pressure in a child
(2018-12-14)
Purpose:
We describe a case of normal tension glaucoma in the setting of sickle cell disease in a 9-year-old patient with a five-year follow up.
Observations:
A 9-year-old male patient with a history of sickle cell ...
Therapeutic Targeting of mTOR in T-Cell Acute Lymphoblastic Leukemia: An Update
(2018-06-26)
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive blood malignancy that arises from the clonal expansion of transformed T-cell precursors. Although T-ALL prognosis has significantly improved due to the development ...
Therapeutic targeting of CK2 in acute and chronic leukemias
(2018-01)
Phosphorylation can regulate almost every property of a protein and is involved in all fundamental cellular processes. Thus, proper regulation of phosphorylation events is critical to the homeostatic functions of cell ...
TNM cancer staging: can it help develop a novel staging system for type 2 diabetes?
(2018-11-28)
Abstract: Type 2 diabetes (DM2) constitutes 90%–95% of the diabetes cases and is increasing at an alarming rate in the world. The Centers for Disease Control and Prevention (CDC) esti- mates that more than 29 million people ...
Variation in female aggression in 2 three-spined stickleback populations with female throat and spine coloration
(2018-03-07)
Despite growing interest in female ornament evolution, we still have a rudimentary understanding of female display traits relative to similar traits in males. Under one popular adaptive scenario, fe- male ornaments are ...
The Plight of the Minority Resident Physician— Similar Challenges in a Different World
(2018-09-28)
In the article “Minority Resident Physicians’ Views on the Role of Race/Ethnicity in Their Training Experiences in the Workplace,” Osseo-Asare et al1 report a qualitative approach to teasing out the plight of underrepresented ...
The Populus holobiont: dissecting the effects of plant niches and genotype on the microbiome
(2018-02-12)
Background: Microorganisms serve important functions within numerous eukaryotic host organisms. An understanding of the variation in the plant niche-level microbiome, from rhizosphere soils to plant canopies, is imperative ...
The influence of impact-based severe weather warnings on risk perceptions and intended protective actions
(2018-04-03)
This paper presents the results of an online survey of the New Zealand public (n = 1364), conducted in 2015, that tested the influence of impact-based severe weather warnings on risk perceptions and intended protective ...
Time course metabolome of Roux-en-Y gastric bypass confirms correlation between leptin, body weight and the microbiome
(2018-05-31)
Roux-en-Y gastric bypass (RYGB) is an effective way to lose weight and reverse type 2 dia- betes. We profiled the metabolome of 18 obese patients (nine euglycemic and nine diabet- ics) that underwent RYGB surgery and seven ...