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Factors Associated with Discharge to a Skilled Nursing Facility after Transcatheter Aortic Valve Replacement Surgery
(2018-12-28)
An assumption regarding transcatheter aortic valve replacement (TAVR), a minimally invasive procedure for treating aortic stenosis, is that patients remain at, or near baseline and soon return to their presurgical home to ...
Glaucomatous optic disc changes despite normal baseline intraocular pressure in a child
(2018-12-14)
Purpose:
We describe a case of normal tension glaucoma in the setting of sickle cell disease in a 9-year-old patient with a five-year follow up.
Observations:
A 9-year-old male patient with a history of sickle cell ...
Top-down pulses reduce prey population sizes and persistence
(2018-06-19)
Resource pulses are well documented and have important consequences for population dynamics relative to continuous inputs. However, pulses of top-down factors (e.g. predation) are less explored and appreciated in the ...
Effects of cardiomyopathy-linked mutations K15N and R21H in tropomyosin on thin-filament regulation and pointed-end dynamics
(2018-11-14)
Missense mutations K15N and R21H in striated muscle tropomyosin are linked to dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM), respectively. Tropomyosin, together with the troponin complex, regulates ...
Effectiveness of a Total Meal Replacement Program (OPTIFAST Program) on Weight Loss: Results from the OPTIWIN Study
(2018-11-13)
Objective: The aim of this study was to test the effectiveness of the OPTIFAST program (OP), a total meal replacement dietary intervention, compared with a food-based (FB) dietary plan for weight loss. Methods: Participants ...
Diversity in warning coloration: selective paradox or the norm?
(2018-08-27)
Aposematic theory has historically predicted that predators should select for warning signals to converge on a single form, as a result of frequency‐dependent learning. However, widespread variation in warning signals is ...
Cutaneous adverse reactions in B-RAF positive metastatic melanoma following sequential treatment with B-RAF/MEK inhibitors and immune checkpoint blockade or vice versa. A single-institutional case-series
(2018-12-16)
Background
With the advent of immune-checkpoint inhibitors and targeted treatments (TT), there have been unprecedented response rates and survival in advanced melanoma, but the optimal sequencing of these two treatments ...
Venous varices of the heart: a case report of spontaneous coronary sinus thrombosis with persistent left superior vena cava
(2018-08-16)
Absence of coronary sinus (CS) ostium and presence of a persistent superior left vena cava (PLSVC) are rare congenital anomalies.1 We report a case of spontaneous CS thrombosis with PLSVC associated with new-onset atrial ...
Adolescent smoking: The relationship between cigarette consumption and BMI
(2018-12-07)
Background:Studies relating cigarette smoking and body weight yield conflicting results. Weight-lowering effects in women and men have been associated with smoking, however, no effects on weight have been proven.This study ...
Step-wise evolution of complex chemical defenses in millipedes: a phylogenomic approach
(2018-02-16)
With fossil representatives from the Silurian capable of respiring atmospheric oxygen, millipedes
are among the oldest terrestrial animals, and likely the first to acquire diverse and complex chemical defenses against ...