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Feasibility Study of Dual Energy Radiographic Imaging for Target Localization in Radiotherapy for Lung Tumors
(2014)
Purpose
Dual-energy (DE) radiographic imaging improves tissue discrimination by separating soft from hard tissues in the acquired images. This study was to establish a mathematic model of DE imaging based on intrinsic ...
A new assessment model for tumor heterogeneity analysis with [18]F-FDG PET images
(2016-01)
It has been shown that the intratumor heterogeneity can be characterized with quantitative analysis of the [18]F-FDG PET image data. The existing models employ multiple parameters for feature extraction which makes it ...
Resolving power of diffraction imaging with an objective: a numerical study
(2017-05)
Diffraction imaging in the far-field can detect 3D morphological features of an object for its coherent nature. We describe methods for accurate calculation and analysis of diffraction images of scatterers of single and ...
Role of Blood Cytokine Levels and Adiposity in Myocardial Infarction Recurrence
(2018-05)
Risk factors for myocardial infarction (MI) are important as cardiovascular disease is the leading cause of death. In fact, approximately one third of adults having an MI will have another in six years. The purpose of this ...
Four-Dimensional In Vivo Dosimetry By Dose Reconstruction Using Continuous Epid Images And Phase Sorting Method
(East Carolina University, 2015)
In vivo dosimetry is widely used for patient specific dose evaluation and treatment verification in external beam radiation therapy (EBRT). There is a growing interest in using an electronic portal imaging device (EPID) ...
MODIFICATION OF CELL SURVIVAL RATES BY CERIUM OXIDE NANOPARTICLES FOR EXPOSURE TO PROTON RADIATION
(East Carolina University, 2017-05-03)
Radiation therapy is a well-established and widely used treatment for a variety of malignancies in the human body. Current radiotherapy methods most frequently use x-rays to deliver a lethal dose to tumors with sufficient ...
Protection and Sensitization of Human Cells to Proton Radiation by Cerium Oxide Nanoparticles
(East Carolina University, 2017-07-17)
In radiation therapy for the treatment of cancer, there is demand for novel approaches that will improve tumor cell killing while protecting healthy tissue. One such approach that has shown considerable promise is the ...
Biophysical Mechanisms Mediating Fibrin Fiber Lysis
(2017-05-28)
The formation and dissolution of blood clots is both a biochemical and a biomechanical process. While much of the chemistry has been worked out for both processes, the influence of biophysical properties is less well ...
Quantitative analysis and comparison of 3D morphology between viable and apoptotic MCF-7 breast cancer cells and characterization of nuclear fragmentation
(2017-09-08)
Morphological changes in apoptotic cells provide essential markers for defining and detection
of apoptosis as a fundamental mechanism of cell death. Among these changes, the
nuclear fragmentation and condensation have ...
Mutation of tandem repeats in fibrin's alpha-C region
(East Carolina University, 2018-01-19)
Cardiovascular problems such as myocardial infarctions and emboli are the number one killers in the United States. These health concerns arise from blood clotting unnecessarily in the veins or arteries. Studies have shown ...