RSS 1.0Honors College
Recent Submissions
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Elucidation of allosteric behavior and enzyme-effector complexes of human 15-lipoxygenase-2 through hydrogen-detuerium exchange mass spectrometry
(East Carolina University, 2019-05-03)The enzymatic activity of human 15-lipoxygenase-2 (15-LOX-2) has been implicated in human inflammatory diseases such as atherosclerotic cardiovascular disease and plays an important role in maintaining homeostasis. 15-LOX-2 ... -
ANDROGEN AND PROGESTERONE RECEPTORS KNOCKOUTS IN ZEBRAFISH AFFECT AGGRESSION AND SOCIAL DOMINANCE
(East Carolina University, 2019-05-03)ABSTRACT - There is circumstantial evidence that steroids, such as androgens and progesterone, play roles in aggression and social behaviors in vertebrates. However, the genetic basis for these behaviors needs to be further ... -
Development of a Method for the Determination of Bisphenol A in Vervet Monkey Hair using LC-MS/MS and LC-UV/Vis
(East Carolina University, 2019-05-03)No methods for estimating levels of anthropogenic disturbance on non-human primate (NHP) populations were identified within the literature. Such a method would allow for the assessment of human impact on NHP populations. ... -
SYSTEMATIC BENZOATE PRESERVATIVE ANALYSIS IN POPULAR BEVERAGES
(East Carolina University, 2019-05-02)Introduction Benzoic acid derivatives (such as sodium benzoate and potassium benzoate) are frequently added to commercial beverages as a preservative. FDA regulations prohibit benzoate levels from exceeding 1000 mg/L (0.1% ... -
The Generation of an Antibody to the Bearded-Ear Protein in Maize
(East Carolina University, 2019-05-02)Flowers are essential for plants to reproduce and also produce seeds and fruits that are consumed as food. Zea mays (maize) is both a staple crop and serves as a model for other grass species. In maize, male and female ... -
Beneficial neurocognitive effects of chronic naltrexone treatment in rats poisoned with the sarin analog diisopropylfluorophosphate
(East Carolina University, 2019-05-02)Accidental poisoning with organopesticides utilized for agricultural purposes is commonly seen in rural communities, including many areas of eastern NC. It is documented that chronic nerve damage, including cerebral ... -
Molecular chaperone Tetratricopeptide repeat protein 2 (Tpr2) is essential for germline stem cell self-renewal and timely cyst divisions in Drosophila melanogaster oogenesis
(East Carolina University, 2019-05-02)Steroid hormones influence cell proliferation and cell fate in developing and injured tissues. Although steroid hormone signaling has been well-studied, the precise mechanisms by which cells specifically receive steroid ... -
BEHAVIORAL STUDY OF GOBIOSOMA BOSC IN RESPONSE TO VISUAL IMPLANT ELASTOMER (VIE) TAGGING
(East Carolina University, 2019-05-02)The naked goby (Gobiosoma bosc) is a small benthic fish that inhabits western Atlantic estuaries, where it ranges from Massachusetts to Mexico. Previous work has found limited gene flow between and among populations of G. ... -
AN EXAMINATION OF POTENTIAL NEURAL DIFFERENCES IN EXERCISERS AND NON-EXERCISERS: AN EEG STUDY
(East Carolina University, 2019-05-02)Within the United States, obesity rates continually increased from 1999 to 2016 (CDC, 2017). This is particularly concerning due to the fact that the American government has put out abundant amounts of information on these ... -
Influence of Modified Starches on Mental Performance and Physical Endurance Following Exhaustive Exercise
(East Carolina University, 2019-05-02)Slow-releasing carbohydrates may delay the effects of fatigue after exhaustive exercise. The purpose of this study was to observe the influence that hydrothermally modified starches (HMS) and traditional maltodextrin (MAL) ... -
TESTING THE EFFECTIVENESS OF AN ONLINE PARENTAL BEREAVEMENT PROGRAM
(East Carolina University, 2019-05-02)Experiencing the death of a child can impact multiple aspects of the parent’s overall health, composed of physical, mental, and social health, and can even impact the parent’s ability to sleep (Dias et al., 2017). The ... -
Developing and Testing the Functionality and Usability of a Bereavement Support Web-based Link for Bereaved Parents
(East Carolina University, 2019-05-02)In 2017, there were approximately 9,376 deaths of children aged 1-14 years (Centers for Disease Control and Prevention, 2017). Family members experience immense grief as they transition to a life without their child. ... -
THE EFFECTS OF AEROBIC EXERCISE INTENSITIES ON CENTRAL BLOOD PRESSURE IN OVERWEIGHT AND OBESE AFRICAN AMERICANS
(East Carolina University, 2019-05-02)African Americans are at an increased risk of cardiovascular disease and type 2 diabetes compared to their Caucasian counterparts. According to the 2018 American Heart Association report, nearly half of all African American ... -
The Role of the Melanocortin-1 Receptor Gene in Müllerian Mimic Ranitomeya imitator
(East Carolina University, 2019-05-02)The Peruvian poison dart frog Ranitomeya imitator has undergone a Müllerian mimetic radiation, which means that this species has evolved color patterns that mimic three other poison dart frogs in different geographic regions ... -
Using Heart Rate Variability to Assess Resident Stress During Central Venous Catheter Simulation
(East Carolina University, 2019-04-30)Simulation based central venous catheter (CVC) training has been shown to result in fewer needle passes and complications. Heart rate variability (HRV) has been shown to be effective in identifying stress and self-confidence ... -
The Influence of Depression on Medication Adherence Among Cancer Survivors
(East Carolina University, 2019-04-30)Cancer survivorship is defined as “any person living with, through, and beyond cancer” which encompasses over 15.5 million Americans. Although rates of survivorship have increased, cancer survivor adherence rates are still ... -
Design, Expression, and Characterization of a Bifunctional Protein Chimera for Applications in Molecular Biology
(East Carolina University, 2019-05-02)There are many different methods of protein capture that are used to immobilize proteins on solid supports while still maintaining their overall function. In this study, the binding interaction between streptavidin and ... -
AGE-DEPENDENT STUDY OF PATHOLOGICAL PROGRESSION OF ALZHEIMER’S DISEASE IN HIPPOCAMPAL AND CORTICAL TISSUE OF HUMAN AND AN AD MOUSE MODEL
(East Carolina University, 2019-05-02)Degeneration of synaptic plasticity plays a critical role in Alzheimer’s disease (AD) pathogenesis. Recent studies have suggested that neuroinflammation may contribute to this degeneration by disrupting the amyloid metabolism ... -
Consequences Of Long-Term Fertilization on Wetland Microbial Function
(East Carolina University, 2019-05-02)Anthropogenic disturbances have led to increased deposition of nitrogen (N) and phosphorus (P) into soils. Nutrient enrichment of soils is known to increase plant biomass and also increase rates of microbial litter ... -
REDUCING ENVIORNMENTALLY INDUCED BIRTH DEFECTS WITH PRENATAL SUPPLEMENTION
(East Carolina University, 2019-05-02)Pollutant exposure during development has been shown to induce developmental malformations. For example, penis deformities are the most common birth defects occurring in boys born in the United States, and are associated ...