Browsing Honors College by Author "Biomedical Sciences"
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ASSESSMENT OF MITOCHONDRIAL ENERGETICS IN A SKELETAL MUSCLE RESISTANT TO HYPOXIA.
Mooney, Serena (East Carolina University, 2021-04-23)Skeletal muscle is dependent upon oxygen (O2) to maintain normal physiological function by acting as the final electron acceptor in the mitochondria during ATP production. Loss of O2 tension (i.e. hypoxia) leads to the ... -
EXERCISE AND DIET PROGRAMS DROSOPHILA SIMULANS OFFSPRING METABOLIC PHENOTYPE
Johnson, Aaron M (East Carolina University, 2021-04-23)Obesity in pediatric patients has increased significantly in recent decades, along with susceptibility to Type 2 Diabetes (T2D), cardiovascular disease, cancer, and mortality. The relative contribution of genetic and ... -
Predicting HBZ Interaction with BATF3 Enhancer Regions Through ChIP-seq
Luke, Mikayla (East Carolina University, 2021-05-28)Human Lymphotropic Virus Type 1 (HTLV-1) is a complex retrovirus that causes Adult T-cell Leukemia (ATL), an often-fatal form of cancer characterized by uncontrolled proliferation of infected CD4+ T-cells. The viral protein ... -
The effects of high-fat diet induced insulin resistance on cardiac structure, function, and lipid profile
Sarathy, Brinda (East Carolina University, 2021-04-23)Intracardiac injection of recombinant EphrinA1-Fc immediately following coronary artery ligation in mice reduces infarct size in both reperfused and non-reperfused myocardium. These protective effects occurred via modulation ...