Browsing Health Sciences Campus by Title
Now showing items 110-129 of 2643
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Analysis of the mutation in cutaneous melanoma patients with occupational sun exposure
(2014-03)Sun-exposure is one of the risk factors associated with the development of a cutaneous neoplasm. In melanoma, the Ras-Raf-MEK-ERK (MAPK) signaling pathway is constitutively activated through multiple mechanisms, including ... -
An Analysis of the Process of Nurse Practitioners Moving to Full Practice Authority and Developmental Summary of Practice Implications to Assist Others in the Future
(2017-04-27)Abstract Nurse Practitioners (NPs) have assumed a progressively important role as primary care providers for millions of Americans. Full practice authority (FPA) is the collection of state practice and licensure laws ... -
Analysis of the Zinc Finger Domain of TnpA, a DNA Targeting Protein Encoded by Mobilizable Transposon Tn4555
(East Carolina University, 2007-07)The mobilizable transposon Tn4555, found in Bacteroides spp., is an important antibiotic resistance element encoding a broad spectrum beta-lactamase. Tn4555 is mobilized by conjugative transposons such as CTn341 which can ... -
ANALYSIS OF TRANSGENIC MOUSE MODELS TO STUDY MAMMALIAN SPERMATOGONIA
(East Carolina University, 2018-07-24)Spermatogenesis in the mammalian testis results in the daily production of millions of spermatozoa. This developmental process is founded upon the actions of a small population of spermatogonial stem cells (SSCs). As SSCs ... -
Anatomical and Physiological Changes Following Primary Palatoplasty Using the Buccal Flap Approach
(East Carolina University, 2021-04-14)Individuals born with cleft palate typically undergo primary palatoplasty between 6-12 months of age to repair their palate. Traditional primary palatoplasty surgical techniques include the V-Y pushback, the intravelar ... -
Anatomical-Molecular Distribution of EphrinA1 in Infarcted Mouse Heart Using MALDI Mass Spectrometry Imaging
(2018-01-05)EphrinA1 is a tyrosine kinase receptor localized in the cellular membrane of healthy cardiomyocytes, the expression of which is lost upon myocardial infarction (MI). Intra-cardiac injection of the recombinant form of ... -
Anatomy Touch Table Project
(2018-05-22)Objectives : The library has seen great usage in its anatomical model collection but struggles to meet patron demand during peak times. The objective of this project was to improve patron experience and utilization of ... -
Anesthesia Providers’ Perceptions of Perioperative Temperature Monitoring: A DNP Project
(2022-11-25)Perioperative temperature monitoring is a standard of care and is important to prevent inadvertent perioperative hypothermia (IPH) and the associated increased risks. IPH is defined as a temperature of less than 36° Celsius ... -
Animal Viruses, Bacteria, and Cancer: A Brief Commentary
(2014-02)Animal viruses and bacteria are ubiquitous in the environment. However, little is known about their mode of transmission and etiologic role in human cancers, especially among high-risk groups (e.g., farmers, veterinarians, ... -
Another dimension to the black Diaspora. Diet, disease, and racism
(East Carolina University, 1983-07) -
Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants
(East Carolina University, 2008-07)Many chemotherapy drugs are known to cause significant clinical neurotoxicity, which can result in the early cessation of treatment. To identify and develop more effective means of neuroprotection it is important to ... -
Anti-growth properties of BAY 41-2272 in vascular smooth muscle cells
(East Carolina University, 2009-02)Vascular smooth muscle (VSM) growth is integral in the pathophysiology of blood vessel diseases, and identifying approaches that have capacity to regulate VSM growth is critically essential. Cyclic nucleotide signaling has ... -
Antibiotic Stewardship
(2019-04-22)Antibiotic resistance is among the greatest public health threats today. However, antibiotics are being prescribed when not indicated at astoundingly high rates. A gap exists between understanding when to prescribe antibiotics ... -
Antibiotic Stewardship: Implementing the Use of Centor Scoring for Pharyngitis
(2022-07-18)Antibiotics are prescribed at an alarmingly high rate and can lead to antibiotic resistance. Pharyngitis is one of the more common complaints seen in outpatient clinics and too often patients are sent home with antibiotics ... -
Antigen-specific tolerogenic vaccines inhibit autoimmune disease in a rodent model of multiple sclerosis
(East Carolina University, 2010)Multiple sclerosis (MS) is considered to be a T cell-mediated autoimmune disease directed against myelinated nerves within the central nervous system. Current therapies available to MS patients have low efficacy and are ... -
Apigenin prevents chemically-induced skin tumor formation and inhibits COX-2 expression and activity in SKH-1 mouse epidermis
(East Carolina University, 2012)The most common type of cancer in the United States is non-melanoma skin cancer (NMSC), with an estimated two million new cases diagnosed each year. Numerous malignancies including NMSC, colon, breast, and prostate cancer ...