Browsing Health Sciences Campus by Title
Now showing items 1123-1142 of 2643
-
Identification of a circular intermediate in the transfer and transposition of Tn4555, a mobilizable transposon from Bacteroides spp.
(East Carolina University, 1993-05)Transmissible cefoxitin (FX) resistance in Bacteroides vulgatus CLA341 was associated with the 12.5-kb, mobilizable transposon, Tn4555, which encoded the 13-lactamase gene cfxA. Transfer occurred by a conjugation-like ... -
Identification of a novel Leucine-rich repeat protein and candidate PP1 regulatory subunit expressed in developing spermatids
(East Carolina University, 2008-01-31)Background: Spermatogenesis is comprised of a series of highly regulated developmental changes that transform the precursor germ cell into a highly specialized spermatozoon. The last phase of spermatogenesis, termed ... -
Identification of Biomarkers in Non-Small Cell Lung Cancer Patients Treated with PD-1 Monoclonal Antibody Immunotherapy
(East Carolina University, 2018-08-22)Cancer immunotherapy works by taking a patient's existing immune system and priming it to recognize cancer cells in order for immune cells to mount an effective response to the disease. This is a less invasive means of ... -
Identification of cytosolic phosphodiesterases in the erythrocyte: A possible role for PDE5
(2011)Background Within erythrocytes (RBCs), cAMP levels are regulated by phosphodiesterases (PDEs). Increases in cAMP and ATP release associated with activation of β-adrenergic receptors (βARs) and prostacyclin receptors ... -
Identification of E2F1 as a positive transcriptional regulator for delta-catenin
(East Carolina University, 2008-05-02)Delta-Catenin is upregulated in human carcinomas. However, little is known about the potential transcriptional factors that regulate delta-catenin expression in cancer. Using a human delta-catenin reporter system, we have ... -
Identification of Extracellular d-Catenin Accumulation for Prostate Cancer Detection
(East Carolina University, 2009-03-01)BACKGROUND—Prostate cancer is the second leading cause of cancer death in men, and early detection is essential to reduce mortality and increase survival. δ-Catenin is a unique β-catenin superfamily protein primarily ... -
Identification of Factors Associated with the Development and Decay of Heterologous Tolerance to Morphine in the Guinea Pig
(East Carolina University, 2016-05-03)It is believed that the heterologous tolerance that develops upon chronic exposure to morphine is the result of adaptive changes in the cellular signaling pathways associated with the [mu] opioid receptor. Proposed adaptive ... -
Identification of Residual Neuromuscular Blockade in Post-Surgical Patients
(2017-11-19)Background: Many surgical procedures require administration of nondepolarizing neuromuscular blocking (NDNMB) agents. NDNMBs are typically reversed when surgery ends, allowing function to be restored. With more precise ... -
Identification, characterization, and gene expression analysis of nucleotide binding site (NB)-type resistance gene homologues in switchgrass
(2016-11-08)Abstract Background Switchgrass (Panicum virgatum L.) is a warm-season perennial grass that can be used as a second generation bioenergy crop. However, foliar fungal ... -
Identification, cloning and functional characterization of novel beta-defensins in the rat (Rattus norvegicus)
(East Carolina University, 2006-02-04)Background beta-defensins are small cationic peptides that exhibit broad spectrum antimicrobial properties. The majority of beta-defensins identified in humans are predominantly expressed in the male reproductive tract ... -
Identifying Barrett's Esophagus Risk in a Primary Care Setting
(2020-04-24)Barrett’s esophagus incidence has been on the rise for the past four decades. Early identification of Barrett’s esophagus is essential to preventing the morbidity and mortality associated with esophageal adenocarcinoma, a ... -
Identifying Delirium in the Geriatric Population
(2021-04-25)Delirium is a severe change in brain function that can have short and long-term consequences for the hospitalized geriatric patient. Untreated delirium can lead to increased lengths of stay, falls, reduced function ... -
Identifying Patient Education Needs in Hypertension Management
(2019-04-23)Purpose: Hypertension is one of the most commonly treated chronic diseases by primary care providers, with approximately half of those patients being uncontrolled. The purpose of this DNP quality improvement project is to ... -
The immune and neurological impacts of developmental Bisphenol A exposure in a C57bl/6 mouse model
(East Carolina University, 2014)Environmental exposure to exogenous agents during critical time points of development may be associated with the onset of deleterious effects, including immune and neurological disorders. Numerous studies have shown that ... -
Impact of a Nurse-Led Early Mobility Protocol in Postoperative General Surgery Older Adults on Medical-Surgical Units
(2021-07-16)The older population is rapidly growing due to increased longevity in the United States. With these changing demographics, the healthcare system must be prepared to provide quality care in respect to postoperative mobility ... -
The Impact of a Vocational Counseling Based Substance Abuse Intensive Outpatient Program upon Work and Well-Being: A Pilot Study
(East Carolina University, 2011)Even though recovery from Substance Use Disorders (SUDs) involves changes among a number of life domains, services have traditionally focused on abstinence from substances. Cursory attention is placed on holistic treatment ...