Browsing Health Sciences Campus by Title
Now showing items 2412-2431 of 2642
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TGF-β Signaling, Via Smad3, Mediates Notch Pathway-Induced Stemness and Epithelial to Mesenchymal Transition in Colon Cancer Cells
(East Carolina University, 2017-08-21)Late stage colorectal cancer (CRC) remains a challenging disease to treat due to several factors including stemness and epithelial to mesenchymal transition (EMT). Dysfunctional signaling pathways in CRC contribute to these ... -
Th1 Adjuvant N-Acetyl-d-Glucosamine Polymer Up-Regulates Th1 Immunity but Down-Regulates Th2 Immunity against a Mycobacterial Protein (MPB-59) in Interleukin-10-Knockout and Wild-Type Mice
(East Carolina University, 2001-10)Treatment of mice with heat-killed (HK) Mycobacterium bovis BCG or 1- to 10-μm chitin particles (nonantigenic N-acetyl-d-glucosamine polymers) is known to induce innate immune responses, including gamma interferon (IFN-γ) ... -
THE AFFORDABLE CARE ACT, PUBLIC HEALTH ACCREDITATION, AND COMMUNITY HEALTH ASSESSMENT IN NORTH CAROLINA: 2007-2017
(East Carolina University, 2019-04-25)This study explored the reporting of health equity issues in public health-led community health assessments (CHAs) and the reporting of measurable outcomes in the public health-led community health assessments (CHIPs). ... -
The Assessment of Muscle Oxygen Saturation in Students During Maximal VO2 Exercise and High Intensity Intervals
(East Carolina University, 2017-04-28)The advancement of human performance benefits from state-of-the-art technology to improve the ability to monitor and evaluate physiological adaptations in athletes. Previously validated as a reliable tool for measuring ... -
The C-terminus of Troponin T Modulates Calcium Regulation of Actin-Myosin Interactions
(East Carolina University, 2019-05-02)The highly conserved terminal fourteen C-terminal residues of troponin T play a novel role in the regulation of striated muscle contraction. Elimination of the terminal fourteen residues of the C-terminal region of troponin ... -
The Circadian Rhythm and its Role in the Dynamic Dopamine Neuron Phenotype
(East Carolina University, 2021-05-04)The circadian rhythm is strongly implicated in many neuropsychiatric and neurodegenerative disorders, all of which are associated with altered dopamine (DA) neurotransmission in the substantia nigra and ventral tegmental ... -
THE DISTINCT ROLES OF TWO eIF4E ISOFORMS AND THEIR COGNATE 4EIPS IN THE GERMLINE OF C. elegans
(East Carolina University, 8/5/2020)Biological information becomes functional at the step of mRNA translation when the protein product is synthesized. Translational regulation of mRNAs is critically important for proper modulation of gene expression in germ ... -
The Effect of Brief Sex Offender Training on the Graduate Counseling Students’ Scores on the Discrete Emotions Questionnaire and Working Alliance Inventory
(East Carolina University, 2022-04-26)Clinicians who treat sex offenders commonly struggle with the tension between conceptualizing them as rehabilitative or instinctively predatory. On the one hand, there is the well-intended goal of forming an alliance with ... -
THE EFFECT OF COMMUNITY OF INQUIRY IN THE DEVELOPMENT OF EVIDENCED-BASED NURSING COMPETENCIES FOR THE RN-BSN PROGRAMS
(East Carolina University, 2017-12-12)Due to the increasing complexity of patient care, highly educated nurses are needed to improve the quality of care and promote positive patient outcomes through Evidenced-Based Practice (EBP). In order to meet Institute ... -
The Effect Of Fine Arts on Language and Literacy Skills in Children
(East Carolina University, 2018-05-01)Abstract Current techniques of teaching literacy to elementary school students are commonly limited to the use of standard reading programs such as Macmillan, McGraw Hill and Houghton (LaJevic, 2013). Although systematic, ... -
The Effect of Noise Exposure on Auditory Threshold, Otoacoustic Emissions, and Electrocochleography
(East Carolina University, 2016-07-25)Noise exposure is the second leading cause of acquired sensorineural hearing loss and is one of the most common occupational and environmental hazards. Examining changes in behavioral thresholds has long been the standard ... -
The Effectiveness of Interactive Metronome® as a Tool to Improve Cognition and Motor Performance in Healthy Older Adults in Eastern North Carolina
(East Carolina University, 2016-12-15)The purpose of this study was to measure the effectiveness of the Interactive Metronome (IM) in improving cognitive and motor performance in healthy older adults. As the aging adult population continues to rise, it is ... -
THE EFFECTIVENESS OF USING AN INTERACTIVE DRIVING SIMULATOR TO IMPROVE DRIVING SKILLS AND ABILITIES FOR TEENS AND YOUNG ADULTS WITH AUTISM SPECTRUM DISORDER WITHIN THE CONTEXT OF A DRIVING BOOTCAMP
(East Carolina University, 2016-12-15)Purpose: The purpose of this study was to determine the effectiveness of the interactive driving simulator as an intervention tool for teens and young adults with Autism Spectrum Disorder. Method: A pretest/post-test ... -
The Effectiveness of Visual Scanning Training to Improve Functional Performance Poststroke: A Case Study in Eastern North Carolina
(East Carolina University, 2018-06-18)Rationale: Although an abundance of research exists regarding overall rehabilitation interventions poststroke, there is a lack of evidence for treatment of visual deficits. Additionally, eye tracking glasses may be used ... -
The Effects of an Equine Assisted Learning Supervision Intervention on Counselors’-in-Training Performance Anxiety, Counseling Self-Efficacy, and Supervisory Working Alliance
(East Carolina University, 2017-12-12)Due to the complexity of the counseling process, counselors-in-training often experience performance anxiety when entering the counseling profession. Research shows that higher counseling self-efficacy (the belief in oneself ...