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Now showing items 586-605 of 2641
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Differential regulation of the attachment of KSHV infected human B cells to ECM by KSHV encoded gB and cellular alpha-V integrins
(East Carolina University, 2008-07)Kaposi’s sarcoma-associated herpesvirus (KSHV) has two modes replication: latent and lytic replication. Reactivation from latency is dictated, in part, by the cell cycle. Herein, we have attempted to delineate the importance ... -
Differentiation-dependent Requirement of Tsix long non-coding RNA in Imprinted X-chromosome Inactivation
(2014-06)Imprinted X-inactivation is a paradigm of mammalian transgenerational epigenetic regulation resulting in silencing of genes on the paternally-inherited X-chromosome. The pre-programmed fate of the X-chromosomes is thought ... -
Diffusion and perfusion weighted magnetic resonance imaging for tumor volume definition in radiotherapy of brain tumors
(2016-09-21)Abstract Accurate target volume delineation is crucial for the radiotherapy of tumors. Diffusion and perfusion magnetic resonance imaging (MRI) can provide functional information about brain tumors, and they ... -
DINITROBENZENES STIMULATE ELECTRON FLUX WITHIN NEURONAL NITRIC OXIDE SYNTHASE IN THE ABSENCE OF CALMODULIN
(2011)Efficient electron transfer and conversion of L-arginine to L-citrulline and nitric oxide (NO●) by neuronal nitric oxide synthase (nNOS) requires calmodulin (CaM) binding. The present study focused on electron transfer ... -
Direct Inhibition of RNAse T2 Expression by the HTLV-1 Viral Protein Tax
(2011-08)Adult T-cell leukemia (ATL) is one of the primary diseases caused by Human T-cell Leukemia Virus type 1 (HTLV-1) infection. The virally-encoded Tax protein is believed to initiate early events in the development of this ... -
Discharge β-Blocker Use and Race after Coronary Artery Bypass Grafting
(2014-04)Introduction: The use of discharge β-blockers after cardiac surgery is associated with a long-term mortality benefit. β-Blockers have been suggested to be less effective in black cardiovascular patients compared with whites. ... -
Discourse Process Training and Attention Process Training 2 in Adults with Traumatic Brain Injury
(East Carolina University, 2019-05-01)Persons with traumatic brain injury (TBI) often present with relatively preserved lexical and grammatical skills but exhibit discourse level deficits which negatively affect functional communication. Discourse following ... -
Discourse Processing in Neurologically Healthy Adults: A Cross-Modal Eye tracking Study
(East Carolina University, 2021-07-20)One of the methods to study discourse comprehension is inference revision. Inferencing can be defined as a controlled, information-generation process that requires deductive reasoning abilities (Kintsch, 1998). Studies ... -
Discourse processing treatment for adults with aphasia.
(East Carolina University, 2015)The general goal of treatment for people with aphasia (PWA) is to improve their ability to communicate, which involves the discourse level. Treatment at this level is not a new concept, and there are many well-established ... -
Discovering mechanisms during spermatogonial differentiation that prepare male germ cells for meiosis
(East Carolina University, 2022-12-05)Spermatogenesis, the male germ cell maturation process, allows men to become and remain fertile for decades. Male fertility relies on fate decisions of different types of spermatogonia – spermatogonial stem cells maintain ... -
Discovery and investigation of a novel role for mitochondrial prohibitin in mitigating acute heart failure in endotoxic shock
(East Carolina University, 2014)Sepsis results in more than 200,000 deaths annually and is the 10th leading cause of death in the United States (US). In spite of significant advances in medical care the mortality rate for sepsis has continued to rise. ...