Browsing Health Sciences Campus by Title
Now showing items 361-380 of 564
-
Off-label Utilization of Antihypertensive Medications in Children
(East Carolina University, 2007-07)Objective— To examine off-label utilization and costs of antihypertensive drugs in children using a national sample of prescription claims. Design— Cross-sectional study. Setting— 2002 Medstat MarketScan Database, a national ... -
Old Testament Skin Problems.
(2007-08-27)Laupus Library History Collections & the Department of Bioethics & Interdisciplinary Studies sponsor the History of Medicine Presentations as an educational service for the East Carolina University community. The Library ... -
Only the Good Die Young: The 1918-1919 Influenza Pandemic
(2010-01-25)Laupus Library History Collections & the Department of Bioethics & Interdisciplinary Studies sponsor the History of Medicine Presentations as an educational service for the East Carolina University community. The Library ... -
Opsonized Virulent Brucella abortus Replicates within Nonacidic, Endoplasmic Reticulum-Negative, LAMP-1-Positive Phagosomes in Human Monocytes
(East Carolina University, 2005-06)Cells in the Brucella spp. are intracellular pathogens that survive and replicate within host monocytes. Brucella maintains persistent infections in animals despite the production of high levels of anti-Brucellaspecific ... -
Oral citrulline as arginine precursor may be beneficial in sickle cell disease: early phase two results.
(East Carolina University, 2001-10)L-Arginine may be a conditionally essential amino acid in children and adolescents with sickle cell disease, particularly as required substrate in the arginine-nitric oxide pathway for endogenous nitrovasodilation and ... -
Orchiectomy or androgen receptor blockade attenuates baroreflex-mediated bradycardia in conscious rats
(East Carolina University, 2006-01)Background: Previous studies have shown that testosterone enhances baroreflex bradycardia. Therefore, conscious unrestrained rats were used to investigate the role of the androgen receptor in the testosterone-mediated ... -
The ornithine decarboxylase gene odc is required for alcaligin siderophore biosynthesis in Bordetella spp.: putrescine is a precursor of alcaligin.
(East Carolina University, 1996-01)Chromosomal insertions defining Bordetella bronchiseptica siderophore phenotypic complementation group III mutants BRM3 and BRM5 were found to reside approximately 200 to 300 bp apart by restriction mapping of cloned genomic ... -
Orphan Glutamate Receptor delta-1 Subunit Required for High-Frequency Hearing
(East Carolina University, 2007-06)The function of the orphan glutamate receptor delta subunits (GluR 1 and GluR 2) remains unclear. GluR 2 is expressed exclusively in the Purkinje cells of the cerebellum, and GluR 1 is prominently expressed in inner ear ... -
Otoconin-90 Deletion Leads to Imbalance but Normal Hearing: A Comparison with Other Otoconia Mutants
(East Carolina University, 2008-04)Our sense of gravitation and linear acceleration is mediated by stimulation of vestibular hair cells through displacement of otoconia in the utricle and saccule (the gravity receptor organ). We recently showed that otoconin-90 ... -
Outpatient Colonoscopy by Rural Family Physicians
(East Carolina University, 2005-03)PURPOSE Five percent of family physicians offer colonoscopy services, either in the office or the hospital, often in rural areas that have no gastroenterologist. Two previous large series have shown the quality and safety ... -
Overcoming resistance to molecularly targeted anticancer therapies: rational drug combinations based on EGFR and MAPK inhibition for solid tumours and haematologic malignancies
(East Carolina University, 2007-06)Accumulating evidence suggests that cancer can be envisioned as a "signaling disease", in which alterations in the cellular genome affect the expression and/or function of oncogenes and tumour suppressor genes. This ... -
Oxidative stress response in an anaerobe, Bacteroides fragilis: a role for catalase in protection against hydrogen peroxide.
(East Carolina University, 1996-12)Survival of Bacteroides fragilis in the presence of oxygen was dependent on the ability of bacteria to synthesize new proteins, as determined by the inhibition of protein synthesis after oxygen exposure. The B. fragilis ... -
Oxytocin Modulation of Zebra Finch Vocal Development
(East Carolina University, 2010)Autism spectrum disorder is associated with deficits in three main behavioral areas: social behaviors, repetitive behaviors, and language abnormalities. Accumulating evidence suggests a potential role for oxytocin signaling ... -
p53 and NGAL: dual regulatory roles in advanced prostate cancer
(East Carolina University, 2011)The development of prostate cancer from small regions of hyperplasia to invasive tumors requires genetic and epigenetic alterations of critical cellular components to aid in the development of cells more adapted for aberrant ... -
Pain Management after Cardiac Surgery
(East Carolina University, 2009)Postoperative pain relief is one of the most important concerns for patients undergoing cardiac surgery and is one of the most clinically challenging problems for nurses. It is widely recognized that postoperative pain can ... -
Participation in Community-Originated Interventions is Associated with Positive Changes in Weight Status and Health Behaviors in Youth
(2012-04-13)Purpose. To assess changes in children’s health behaviors and weight status after participation in community-originated interventions. ... -
A pathomechanical paradigm for treating the injured runner
(http://legeforeningen.no/spesial/Norsk-forening-for-idrettsmedisin-og-fysisk-aktivitet/Norsk-idrettsmedisin/?so=0, 2013)Pathological mechanics are thought to play a role in many common running injuries. A review of the biomechanical literature reveals that a given running injury may be associated with multiple faulty running mechanics. ... -
Patterns of Distress in African American Mothers of Preterm Infants
(East Carolina University, 2009-06)Objective: To examine inter-relationships among stress due to infant appearance and behavior in the NICU, parental role alteration stress in the NICU, depressive symptoms, state anxiety, posttraumatic stress symptoms, and ... -
Paul De Kruif: The Microbe Hunter and Author
(2009-08-31)Laupus Library History Collections & the Department of Bioethics & Interdisciplinary Studies sponsor the History of Medicine Presentations as an educational service for the East Carolina University community. The Library ... -
Pediatric Palliative Care: A Quality Improvement Recommendation
(2015-06)In the United States, there are greater than 500,000 infants and children living with a life-threatening or life-limiting condition. Advances in healthcare allow children with life threatening or life limiting conditions ...