Browsing Health Sciences Campus by Title
Now showing items 967-986 of 2638
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Functions of claudin-7 in human lung cancer
(East Carolina University, 2012)Lung cancer is the second most common cancer and the most common cause of cancer-related death in both men and women in the United States with a very poor overall 5-year survival rate. Nearly 95% of the lung cancer originates ... -
FUNCTIONS OF CLAUDIN-7 IN THE SELF-RENEWAL OF INTESTINAL EPITHELIUM
(East Carolina University, 8/5/2020)Tight junctions (TJ) are located at the most apical region of the junctional complex and contain many integral membrane proteins. Claudin 7 (Cldn7) is a TJ membrane protein located at the apical TJ and basolateral side of ... -
Functions Required for Extracellular Quinolone Signaling by Pseudomonas aeruginosa
(East Carolina University, 2002-12)A set of 30 mutants exhibiting reduced production of the phenazine poison pyocyanin were isolated following transposon mutagenesis of Pseudomonas aeruginosa PAO1. The mutants could be subdivided into those with defects in ... -
The Future of Forsyth County Special Olympics Athlete Physicals
(2021-04-26)The intellectually and developmentally disabled population face many health disparities. Special Olympics North Carolina provides this special population access to healthcare via MedFest events where athlete physicals are ... -
Gaining the PROMIS perspective from children with nephrotic syndrome: a Midwest pediatric nephrology consortium study
(2013)Background and objectives Nephrotic syndrome (NS) represents a common disease in pediatric nephrology typified by a relapsing and remitting course and characterized by the presence of edema that can significantly affect ... -
Gastrogastric fistulas. A complication of divided gastric bypass surgery.
(East Carolina University, 1995-04)Objective This report warns that gastrogastric fistulas may follow the division of the stomach in bariatric surgery. Summary Background Data Although surgery is the most effective therapy for morbid obesity, the ... -
Gene-environment interactions in sarcoidosis
(East Carolina University, 2007-05)Susceptibility to most human diseases is polygenic, with complex interactions between functional polymorphisms of single genes governing disease incidence, phenotype, or both. In this context, the contribution of any ... -
Generation and characterization of the humoral immune response to DNA immunization with a chimeric beta-amyloid-interleukin-4 minigene
(East Carolina University, 2003-12)Active immunization with fibrillar beta-amyloid peptide (AB42) as well as passive transfer of anti-AB antibodies significantly reduces AB plaque deposition, neuritic dystrophy, and astrogliosis in the brain of mutant amyloid ... -
Generational differences in practice site selection criteria amongst primary care physicians.
(2016)Background and Objectives: Generational differences are often viewed as shaping the overall attitudes and actions of different age cohorts. It is essential to understand the motivations and generational differences in ... -
Generational differences in practice site selection criteria amongst primary care physicians.
(2016-01-25)Background and Objectives: Generational differences are often viewed as shaping the overall attitudes and actions of different age cohorts. It is essential to understand the motivations and generational differences in ... -
Generators of mammalian vestibular surface responses to head motion
(East Carolina University, 2012)The linear vestibular sensory evoked potential (VsEP) is thought to be the compound electrical response of peripheral macular neurons and central neural relays, and as such used to directly assess macular function. The ... -
Generic Medications and Blood Pressure Control in Diabetic Hypertensive Subjects
(2013-03)OBJECTIVE To investigate temporal improvements in blood pressure (BP) control in subjects with diabetes and policy changes regarding generic antihypertensives. RESEARCH DESIGN AND METHODS In a cross-sectional study ... -
Genetic and biochemical analysis of a novel Ambler class A β-Lactamase responsible for cefoxitin resistance in Bacteroides species.
(East Carolina University, 1993-05)A clinical isolate of Bacteroides vulgatus was resistant to tetracycline, clindamycin, ampicillin, cephaloridine, cefoxitin, and other 13-lactam antibiotics except imipenem. 13-Lactam resistance was mediated by a ... -
Genetic and hypoxic effects on germline tumor development in caenorhabditis elegans
(East Carolina University, 2013)The process of differentiation of stem cells to committed, progenitor specific cell types is well studied but the reverse process of the dedifferentiation of these committed cells back to the undifferentiated state still ...