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Now showing items 1691-1700 of 2688
FACTORS ASSOCIATED WITH THE EARLY IDENTIFICATION OF SEPSIS
(East Carolina University, 2017-06-02)
The incidence of sepsis is increasing and is one of the most frequent causes of death in hospitals in the United States. Sepsis is a heterogeneous clinical syndrome that is difficult to identify in rapid clinical settings ...
Microglial dysfunction as an early susceptibility to Alzheimer's disease: the exacerbating role of developmental toxicity
(East Carolina University, 2017-07-25)
The association between perturbations to neuroimmune development and susceptibility to adult neurodegenerative diseases, like Alzheimer's disease (AD), may undersore a putative pathogenic role for gradual microglial ...
The Tumor Suppressive Effects of T Cell Death-Associated Gene 8 in Blood Cancers
(East Carolina University, 2017-03-16)
In the early twentieth century Otto Warburg recognized a metabolic phenomenon that transpired in cancer cells, currently known as the Warburg Effect. Warburg discovered cancer cells favor glycolysis rather than oxidative ...
QUANTITATION OF INTERCELLULAR CONNECTIONS BETWEEN SPERMATOGONIA IN THE MOUSE
(East Carolina University, 2017-05-09)
Spermatogonial stem cells (SSCs) are critical in the male reproductive process, as they can either self-renew or proliferate into progenitor cells that differentiate to enter meiosis and eventually form functional sperm. ...
A Provider’s Guide to Weight Loss through Motivational Interviewing
(2017-10-31)
Abstract
Obesity is an epidemic in the United States affecting millions of adults with many considered overweight or obese. An evidence-based quality improvement project was conducted in a primary care office with 33 ...
Targeting Kremen1 Downregulation with RVG-9R/siRNA Complexes in the Triple-Transgenic Mouse Model of Alzheimer’s Disease
(East Carolina University, 2017-07-19)
Alzheimer's disease (AD) is a progressive disease characterized by cognitive decline and memory loss. Memory loss observed in AD results from the loss of neurons and synapses which may be caused by the disruption of the ...
Notch 3 Affects Chemoresistance in Colorectal Cancer via DNA Base Excision Repair Enzymes
(East Carolina University, 2017-07-28)
Approximately 1.2 million cases of colorectal cancer (CRC) arise each year, and 40-50% of CRC patients will reach metastasis. The Notch pathway is known to be dysregulated in CRC, and its relationship with DNA repair ...
A Provider Educational Program Promoting Testicular Cancer Awareness
(2017-11-15)
Abstract
Testicular cancer (TC) is the most common malignancy in males aged 15 to 40. It is estimated that only 3% of men perform Testicular Self-Exam (TSE) and they have little awareness of this disease and how it is ...
Improving Nursing Leadership’s Usage of Real Time, Data-Driven Dashboards
(2017-11-17)
The use of dashboards displaying real-time metrics has been shown to have a positive effect on patient care outcomes. A Plan-Do-Study-Act (PDSA) cycle was conducted to iterate the layout of an existing nursing dashboard ...
Identification of Residual Neuromuscular Blockade in Post-Surgical Patients
(2017-11-19)
Background: Many surgical procedures require administration of nondepolarizing neuromuscular blocking (NDNMB) agents. NDNMBs are typically reversed when surgery ends, allowing function to be restored. With more precise ...