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Single Incision Laparoscopic Ventral Hernia Repair
(2011)
Background and Objectives:
Laparoscopic ventral hernia repair (LVH) requires several skin incisions for trocar placement. We have developed a single incision approach to LVH repair. The technique was introduced in ...
EXPLORING THE ROLE OF ELEVATED LIPID PEROXIDATION AND GLUTATHIONE PEROXIDASE 4 IN METABOLIC SYNDROME AND CARDIAC REMODELING IN OBESITY
(5/16/2016)
Cardiovascular disease continues to be a leading cause of global mortality. Metabolic perturbations including obesity, hyperlipidemia and type II diabetes arising from a western style diet and a more sedentary lifestyle ...
Modulation of experimental autoimmune myocarditis with cytokine-myosin fusion proteins and novel cardiac peptides
(2016-05-16)
Infectious agents that induce cross-reactive myocarditic T cell responses may cause autoimmune inflammation of the heart, dilated cardiomyopathy (DCM), and heart failure. The purpose of this study was to evaluate the ...
Implementing Antibiotic Stewardship in an Ambulatory Urgent Care Setting
(2016-07-09)
Antibiotic prescriptions for the treatment of common viral infections such as acute uncomplicated bronchitis are discouraged because they contribute to both avoidable adverse events and the development of bacterial resistance. ...
Smoking and dietary inadequacy among Inuvialuit women of child bearing age in the Northwest Territories, Canada
(2013)
Objective
The prevalence of smoking in Aboriginal Canadians is higher than non-Aboriginal Canadians, a behavior that also tends to alter dietary patterns. Compared with the general Canadian population, maternal smoking ...
Cannabinoid exposure during zebra finch sensorimotor vocal learning persistently alters expression of endocannabinoid signaling elements and acute agonist responsiveness
(2011)
Background
Previously we have found that cannabinoid treatment of zebra finches during sensorimotor stages of vocal development alters song patterns produced in adulthood. Such persistently altered behavior must be ...
The Combined Influence of Oral Contraceptives and Human Papillomavirus Virus on Cutaneous Squamous Cell Carcinoma
(2011-03)
The vast majority of cutaneous squamous cell carcinoma (CSCC) will occur in those with fair complexion, tendency to burn, and high ultraviolet radiation (UVR) exposure. Organ transplant recipients also are an important ...
EPG5-related Vici syndrome: a paradigm of neurodevelopmental disorders with defective autophagy
(2016-03)
Vici syndrome is a progressive neurodevelopmental multisystem disorder due to recessive mutations in the key autophagy gene EPG5. We report genetic, clinical, neuroradiological, and neuropathological features of 50 children ...
Differentiation-dependent Requirement of Tsix long non-coding RNA in Imprinted X-chromosome Inactivation
(2014-06)
Imprinted X-inactivation is a paradigm of mammalian transgenerational epigenetic regulation resulting in silencing of genes on the paternally-inherited X-chromosome. The pre-programmed fate of the X-chromosomes is thought ...
Patient and Practice Perspectives on Strategies for Controlling Blood Pressure, North Carolina, 2010–2012
(2014)
Introduction
Patient and practice perspectives can inform development of team-based approaches to improving blood pressure control in primary care. We used a community-based participatory research approach to assess patient ...