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Now showing items 11-15 of 15
Effects of psychological stressors and [delta]⁹-THC acutely and chronically on zebra finch song behavior and dendritic spine density
(East Carolina University, 2020-06-22)
This dissertation investigated song performance and dendritic spine density, following acute restraint stress in adult zebra finches and, following chronic mild stress and CB1 receptor partial agonist [delta]⁹-tetrahydrocannabinol ...
INVESTIGATING MECHANISMS REGULATING MAMMALIAN SPERMATOGONIAL DIFFERENTIATION AND MEIOTIC INITIATION
(East Carolina University, 2022-06-27)
Spermatogonia differentiation and meiotic initiation are complex processes essential for male fertility. Despite knowing for nearly 60 years that retinoic acid (RA) is instrumental for successful production of functional ...
PUF-8 and MPK-1: Genetic and Chemical Control of Spermatocyte Dedifferentiation in Caenorhabditis elegans
(East Carolina University, 2021-05-03)
Stem cells face a number of major fate decision during their development: the decision to self-renew or differentiate, and then whether to remain differentiated or dedifferentiate, as occurs in some oncogenesis. A regulatory ...
Fish oil disrupts B cell plasma membrane lateral organization and immunological synapse formation
(East Carolina University, 2012)
Fish oil has immunosuppressive properties that could provide treatment for numerous inflammatory and autoimmune disorders. The primary bioactive components of fish oil, which are the n-3 polyunsaturated fatty acids (PUFAs) ...
THE DISTINCT ROLES OF TWO eIF4E ISOFORMS AND THEIR COGNATE 4EIPS IN THE GERMLINE OF C. elegans
(East Carolina University, 8/5/2020)
Biological information becomes functional at the step of mRNA translation when the protein product is synthesized. Translational regulation of mRNAs is critically important for proper modulation of gene expression in germ ...