Browsing Brody School of Medicine by Title
Now showing items 75-94 of 1483
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Apigenin prevents chemically-induced skin tumor formation and inhibits COX-2 expression and activity in SKH-1 mouse epidermis
(East Carolina University, 2012)The most common type of cancer in the United States is non-melanoma skin cancer (NMSC), with an estimated two million new cases diagnosed each year. Numerous malignancies including NMSC, colon, breast, and prostate cancer ... -
Apigenin Prevents UVB-Induced Cyclooxygenase 2 Expression: Coupled mRNA Stabilization and Translational Inhibition
(East Carolina University, 2007-01)Cyclooxygenase 2 (COX-2) is a key enzyme in the conversion of arachidonic acid to prostaglandins, and COX-2 overexpression plays an important role in carcinogenesis. Exposure to UVB strongly increased COX-2 protein expression ... -
Apparatus and method for measuring physiological characteristics of an intact trachea in vitro
(2011-03-15)Apparatus and methods for measuring smooth muscles responses (relaxation and contraction), transepithelial potential difference, and/or transepithelial impedance of an intact trachea in vitro. In particular embodiments, ... -
Applying Community-Based Participatory Research Partnership Principles to Public Health Practice-Based Research Networks
(2016)With real-world relevance and translatability as important goals, applied methodological approaches have arisen along the participatory continuum that value context and empower stakeholders to partner actively with academics ... -
Arginase Promotes Neointima Formation in Rat Injured Carotid Arteries
(East Carolina University, 2009-04)Objective—Arginase stimulates the proliferation of cultured vascular smooth muscle cells (VSMCs); however, the influence of arginase on VSMC growth in vivo is not known. This study investigated the impact of arginase on ... -
Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics
(2014-09)Sphingosine 1-phosphate (S1P) is a bioactive lipid that is formed by the phosphorylation of sphingosine and catalysed by sphingosine kinase 1 (SK1) or sphingosine kinase 2 (SK2). Sphingosine kinases play a fundamental role ... -
Assessment of the quality of existing patient educational tools focused on sudden cardiac arrest: a systematic evaluation by the Sudden Cardiac Arrest Thought Leadership Alliance
(2013)Background Conveying contemporary treatment options for those at risk of sudden cardiac arrest (SCA) is challenging. The purpose of the present research was to evaluate the quality and usability of available patient ... -
The Association between Trust in Health Care Providers and Medication Adherence among Black Women with Hypertension
(2013-09)Background: Black women have the highest prevalence of hypertension in the world. Reasons for this disparity are poorly understood. The historical legacy of medical maltreatment of Blacks in the U.S. provides some insight ... -
Association of cardiac and vascular changes with ambient PMin diabetic individuals
(2010)Background and Objective Exposure to fine airborne particles (PM2.5) has been shown to be responsible for cardiovascular and hematological effects, especially in older people with cardiovascular disease. Some epidemiological ...