Now showing items 855-874 of 1484

  • Metformin Improves Insulin Signaling in Obese Rats via Reduced IKK Action in a Fiber-Type Specific Manner 

    Bikman, Benjamin Thomas; Zheng, Donghai; Kane, Daniel A.; Anderson, Ethan; Woodlief, Tracey L.; Price, Jesse W.; Dohm, G. Lynis; Neufer, P. Darrell; Cortright, Ronald N. (2010)
    Metformin is a widely used insulin-sensitizing drug, though its mechanisms are not fully understood. Metformin has been shown to activate AMPK in skeletal muscle; however, its effects on the inhibitor of κB kinaseβ (IKKβ) ...
  • Method and apparatus for treating renal disease with hemodialysis utilizing pulsatile pump 

    Bolin, Paul Jr. (2002-08-22)
    A method of removing toxins from blood from a patient in need of such toxin removal includes: providing a countercurrent dialysis filter (20) having a blood compartment and a dialysate compartment separated from the blood ...
  • Method for nerve growth induction 

    DeVanzo, John; Paul, Joseph W. (1993-03-16)
    A composition comprising nerve growth factor and 2-amino-1,1,3-tricyano-1-propene useful for the induction, stimulation, and maintenance of nerve growth, and methods of potentiating choline O-acetyltransferase and tyrosine ...
  • Method for nerve growth induction 

    Da Vanzo, John Paul; Paul, Joseph W. (1993-03-16)
    A composition comprising nerve growth factor and 2-amino-1,1,3-tricyano-1-propene useful for the induction, stimulation, and maintenance of nerve growth, and methods of potentiating choline O-acetyltransferase and tyrosine ...
  • Method for reducing adenosine levels with a dehydroepiandrosterone and optionally a ubiquinone 

    Nyce, Jonathan W. (2000-07-11)
    A method and composition for reducing adenosine levels comprises administering a dehydroepiandrosterone, and optionally a ubiquinone.
  • Method for the microbial decontamination of blood platelets 

    Read, Marjorie S.; Bode, Arthur P.; Summarial, Louis J. (1999-04-06)
    A method for inactivating microbiological contaminants in a human blood platelet preparation is disclosed. The method comprises, first, providing blood platelets, particularly human blood platelets, suspected of being ...
  • Method for the synthesis of 3-substituted indolizine and benzoindolizine compounds 

    Hayford, Anthony; Kaloko, Joseph (2006-07-13)
    A method of making a compound of Formula (I) comprises reacting a compound of Formula (II) with a compound such as R1OH or R1SH, to produce said compound of Formula (I). Compounds of Formula (I) are useful, among other ...
  • Method of detecting cancer using delta-catenin 

    Lu, Qun; Chen, Yan-Hua (2008-11-04)
    The present invention provides a method for detecting or screening for the presence of cancer in a subject. The method comprises obtaining, providing or collecting a tissue or fluid sample (such as a urine sample) from ...
  • Method of inhibiting carcinogenesis by treatment with dehydroepiandrosterone and analogs thereof 

    Nyce, Jonathan W. (1996-06-18)
    A method of combatting cancer in a subject comprising administering to said subject dehydroepiandrosterone (DHEA) or an analog thereof in an amount effective to combat cancer is disclosed in which heart failure induced by ...
  • Method of treating adenosine depletion 

    Nyce, Jonathan W. (1997-08-26)
    A method of treating adenosine depletion in a subject in need of such treatment is disclosed. The method comprises administering to the subject folinic acid or a pharmaceutically acceptable salt thereof in an amount effective ...
  • Method of treating asthma 

    Fisher, Robert H.; Metzger, James; Henriksen, Ruth A. (1996-09-10)
    A method of treating asthma in a subject in need of such treatment comprises contacting Asthma Reversal Factor to the respiratory epithelium of the subject. The active agent is preferably contacted to the subject's respiratory ...
  • Method of treating asthma using IL-8 

    Fisher, Robert H.; Metzger, James (1994-03-01)
    A method of treating asthma in a subject in need of such treatment comprises contacting Interleukin-8 or an active fragment thereof to the respiratory epithelium of the subject. The active agent is preferably human endothelial ...
  • Method of treating disorders characterized by overexpression of cytidine deaminase or deoxycytidine deaminase 

    Nyce, Jonathan W. (2002-08-13)
    A composition, device, kit and method for countering or diagnosing cytidine deaminase or deoxycytidine deaminase over-expression or a disorder associated with it, or an increase in number or toxicity of pro-inflammatory ...
  • Method of treatment using chemotherapy and erythropoietin 

    Anagnostou, Athanasius A.; Sigounas, George (1999-07-13)
    The use of human erythropoietin (EPO) to prevent or treat endothelial injury due to chemotherapy, radiation therapy, mechanical trauma, or to a disease state which damages the endothelium (such as inflammation, heart disease ...
  • Methods and Compositions for Poxvirus A35R Protein 

    Roper, Rachel (2012-11-22)
    The present invention provides methods and compositions for modulating an immune response in a subject, comprising administering to the subject an effective amount of an A35R protein or active fragment thereof of vaccinia ...
  • Methods for Assessing Mitochondrial Function in Diabetes 

    Perry, Christopher G.R.; Kane, Daniel A.; Lanza, Ian R.; Neufer, P. Darrell (2013-04)
    A growing body of research is investigating the potential contribution of mitochondrial function to the etiology of type 2 diabetes. Numerous in vitro, in situ, and in vivo methodologies are available to examine various ...
  • Methods for preventing or treating insulin resistance 

    Neufer, P. Darrell; Anderson, Ethan; Szeto, Hazel (2009-08-13)
    The invention provides methods of preventing or treating insulin resistance in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide having at least one ...
  • Methods of Reducing Myocardial Injury Following Myocardial Infarction 

    Virag, Jitka; Dries, Jessica L. (2014-02-27)
  • Methods of using carnosinol and analogs thereof 

    Anderson, Ethan; Katunga, Lalage; Aldini, Giancarlo (2015-12-17)
    Embodiments of the present invention relate to methods of preventing or treating diabetes, an obesity/diabetes-related condition, insulin sensitivity, heart disease, mitochondrial dysfunction or liver disease comprising ...
  • Methods, systems and computer program products for visualizing anatomical structures and blood flow and perfusion physiology using imaging techniques 

    Cheng, Chen, Jr; Ferguson, T. Bruce; Jacobs, Kenneth Michael; Zhiyong, Peng (2016-04-21)
    Methods for combining anatomical data and physiological data on a single image are provided. The methods include obtaining an image, for example, a raw near-infrared (NIR) image or a visible image, of a sample. The image ...