Now showing items 1-2 of 2

  • Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury 

    Fairbanks, Carolyn A.; Schreiber, Kristin L.; Brewer, Kori L.; Yu, Chen-Guang; Stone, Laura S.; Kitto, Kelley F.; Nguyen, H. Oanh; Grocholski, Brent M.; Shoeman, Don W.; Kehl, Lois J.; Regunathan, Soundararajan; Reis, Donald J.; Yezierski, Robert P.; Wilcox, George L. (East Carolina University, 2000-09-12)
    Antagonists of glutamate receptors of the N-methyl-D-aspartate subclass (NMDAR) or inhibitors of nitric oxide synthase (NOS) prevent nervous system plasticity. Inflammatory and neuropathic pain rely on plasticity, presenting ...
  • CENTRAL SENSORIMOTOR CHANGES DUE TO PERIPHERAL NERVE INJURY: ROLE OF DOPAMINERGICS AND OPIOIDS 

    Schaub, Mandee Kate (East Carolina University, 2022-04-28)
    Chronic neuropathic pain (CNP) is a disease typically resulting from injury to the central or peripheral nervous system. CNP has a prevalence of 12-15% in the population, but current treatments are not highly efficacious ...