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Calcium Dependent CAMTA1 in Adult Stem Cell Commitment to a Myocardial Lineage
(2012)
The phenotype of somatic cells has recently been found to be reversible. Direct reprogramming of one cell type into another has been achieved with transduction and over expression of exogenous defined transcription factors ...
Methods and Compositions for Poxvirus A35R Protein
(2012-11-22)
The present invention provides methods and compositions for modulating an immune response in a subject, comprising administering to the subject an effective amount of an A35R protein or active fragment thereof of vaccinia ...
Informational Odds Ratio: A Useful Measure of Epidemiologic Association in Environment Exposure Studies
(2012)
The informational odds ratio (IOR) measures the post-exposure odds divided by the pre-exposure odds (ie, information gained after knowing exposure status). A desirable property of an adjusted ratio estimate is collapsibility ...
Rituximab therapy in pulmonary alveolar proteinosis improves alveolar macrophage lipid homeostasis
(2012)
Rationale
Pulmonary Alveolar Proteinosis (PAP) patients exhibit an acquired deficiency of biologically active granulocyte-macrophage colony stimulating factor (GM-CSF) attributable to GM-CSF specific autoantibodies. PAP ...
Histological and immunohistochemical features of the spleen in persistent polyclonal B-cell lymphocytosis closely mimic splenic B-cell lymphoma
(2012)
Persistent polyclonal B-cell lymphocytosis (PPBL) is rare and intriguing hematological disorder predominantly reported in young to middle- aged smoking women. It is characterized by persistent moderate polyclonal B-cell ...
Mediastinal neoplasms in patients with Graves disease: a possible link between sustained hyperthyroidism and thymic neoplasia?
(2012)
Background
Anterior mediastinal masses are a rare but well documented finding in Graves disease. The vast majority of these lesions represents benign thymic hypertrophy and regress after treatment of the hyperthyroidism. ...
Time Course of Altered Sensitivity to Inhibitory and Excitatory Agonist Responses in the Longitudinal Muscle-Myenteric Plexus and Analgesia in the Guinea Pig after Chronic Morphine Treatment
(2012-01)
Tolerance that develops after chronic morphine exposure has been proposed to be an adaptive response that develops and decays over a defined time course. The present study examined the development of tolerance to the acute ...
Validation of food store environment secondary data source and the role of neighborhood deprivation in Appalachia, Kentucky
(2012)
Background
Based on the need for better measurement of the retail food environment in rural settings and to examine how deprivation may be unique in rural settings, the aims of this study were: 1) to validate one commercially ...
Hypothermia in trauma patients: predicting the big chill
(2012)
Physicians commonly ignore hypothermia, an often-underappreciated event associated with mortality in trauma patients, in general due to its prevalence and belief that it is secondary to the injury itself (secondary ...