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Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains
(East Carolina University, 2009-02-25)
Mutations in the DJ-1 gene have been linked to autosomal recessive familial Parkinson's disease. To understand the function of DJ-1, we determined the DJ-1 expression in both zebrafish and post mortem human brains. We found ...
Thioredoxin Reductase Is Essential for Thiol/Disulfide Redox Control and Oxidative Stress Survival of the Anaerobe Bacteroides fragilis
(East Carolina University, 2007-11)
Results of this study showed that the anaerobic, opportunistic pathogen Bacteroides fragilis lacks the
glutathione/glutaredoxin redox system and possesses an extensive number of putative thioredoxin (Trx)
orthologs. ...
American Ginseng Modifies 137Cs-Induced DNA Damage and Oxidative Stress in Human Lymphocytes
(East Carolina University, 2009-01-01)
The multifold bioactive medicinal properties of ginseng have been closely linked to its antioxidative ability, which is related to its ginsenoside content. Since the key mechanism of radiation-induced cell death and tissue ...