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Mechanisms Involved in the Cerebrovascular Dilator Effects of N-methyl-D-aspartate in Cerebral Cortex
(East Carolina University, 2007-11)
Glutamate and its synthetic analogues N-methyl-D-aspartate (NMDA), kainate, and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) are potent dilator agents in the cerebral circulation. The close linkage between ...
Role of neuronal nitric oxide in the regulation of vasopressin expression and release in response to inhibition of cathecholamine synthesis and dehydration
(East Carolina University, 2007-10-22)
We used neuronal nitric oxide synthase (nNOS) gene knockout mice to study the effects of
catecholamines and neuronal nitric oxide on vasopressin expression in the hypothalamic
neurosecretory centers. nNOS gene deletion ...