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Contractile activity restores insulin responsiveness in skeletal muscle of obese Zucker rats.
(East Carolina University, 1993-01-15)
Both insulin and contraction stimulate glucose transport in skeletal muscle. Insulin-stimulated glucose transport is decreased in obese humans and rats. The aims of this study were (1) to determine if contraction-stimulated ...
Mechanism for Improved Insulin Sensitivity after Gastric Bypass Surgery
(East Carolina University, 2008-12)
Context: Surgical treatments of obesity have been shown to induce rapid and prolonged improvements in insulin sensitivity. Objective: The aim of the study was to investigate the effects of gastric bypass surgery and the ...
Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4.
(East Carolina University, 1992-02)
A major defect contributing to impaired insulin action in human obesity is reduced glucose transport activity in skeletal muscle. This study was designed to determine whether the improvement in whole body glucose disposal ...