Now showing items 1-3 of 3

  • Characterization of METTL16 as a cytoplasmic RNA binding protein 

    Nance, Daniel J; Satterwhite, Emily R.; Bhaskar, Brinda; Misra, Sway; Carraway, Kristen R.; Mansfield, Kyle D. (2020-01-15)
    mRNA modification by N6-methyladenosine (m6A) is involved in many post-transcriptional regulation processes including mRNA stability, splicing and promotion of translation. Accordingly, the recently identified mRNA ...
  • Hypoxia and Hypoglycemia synergistically regulate mRNA stability 

    Carraway, Kristen R.; Johnson, Ellen M.; Kauffmann, Travis C.; Fry, Nate J.; Mansfield, Kyle D. (2017-07)
    Ischemic events, common in many diseases, result from decreased blood flow and impaired delivery of oxygen and glucose to tissues of the body. While much is known about the cellular transcriptional response to ischemia, ...
  • N6-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression 

    Fry, Nate J.; Law, Brittany A.; Ilkayeva, Olga R.; Carraway, Kristen R.; Holley, Christopher L.; Mansfield, Kyle D. (2018-07-27)
    The mRNA modification N6-methyladenosine (m6A) is involved in many post- transcriptional regulatory processes including mRNA stability and translational efficiency. However, it is also imperative to correlate these processes ...