Browsing Open Access by Author "Yoon, Dong Suk"
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MPK-1/ERK is required for the full activity of resveratrol in extended lifespan and reproduction.
Yoon, Dong Suk; Cha, Dong Seok; Choi, Yoorim; Lee, Jin Woo; Lee, Myon‐Hee (2018-12-21)Resveratrol (RSV) extends the lifespan of various organisms through activation of sirtuin. However, whether RSV-mediated longevity is entirely dependent upon sirtuin is still controversial. Thus, understanding additional ... -
A simple and rapid method for combining fluorescent in situ RNA hybridization (FISH) and immunofluorescence in the C. elegans germline
Yoon, Dong Suk; Pendergrass, DeQwon L.; Lee, Myon-Hee (2016-05-06)Imaging of RNAs and proteins in specific tissues has opened ample avenues to understand gene expression during development. Recently, a fluorescent in situ RNA hybridization (FISH) method has been developed to analyze the ... -
Triclosan Disrupts SKN-1/Nrf2- Mediated Oxidative Stress Response in C. elegans and Human Mesenchymal Stem Cells
Yoon, Dong Suk; Choi, Yoorim; Cha, Dong Seok; Zhang, Peng; Choi, Seong Mi; Alfhili, Mohammad A.; Polli, Joseph Ryan; Pendergrass, DeQwon; Taki, Faten A.; Kapalavavi, Brahmam; Pan, Xiaoping; Zhang, Baohong; Blackwell, T. Keith; Lee, Jin Woo; Lee, Myon-Hee (2017-10-03)Triclosan (TCS), an antimicrobial chemical with potential endocrine-disrupting properties, may pose a risk to early embryonic development and cellular homeostasis during adulthood. Here, we show that TCS induces toxicity ...