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Ages and Stages Questionnaire: a global screening scale | Ages and Stages Questionnaire: una escala de evaluación global
(2017-01-30)
Abstract With standardized screening tools, research studies have shown that developmental disabilities can be detected reliably and with validity in children as young as 4 months of age by using the instruments such as ...
An Expanded Multi-scale Monte Carlo Simulation Method for Personalized Radiobiological Effect Estimation in Radiotherapy: a feasibility study
(2017-03-21)
A novel and versatile “bottom-up” approach is developed to estimate the radiobiological effect of clinic
radiotherapy. The model consists of multi-scale Monte Carlo simulations from organ to cell levels. At cellular level, ...
Antisense oligonucleotide and thyroid hormone conjugates for obesity treatment
(2017-08-24)
Using the principle of antibody-drug conjugates that deliver highly potent cytotoxic agents to
cancer cells for cancer therapy, we here report the synthesis of antisense-oligonucleotides (ASO) and thyroid hormone T3 ...
Drug-resistance in doxorubicin-resistant FL5.12 hematopoietic cells: elevated MDR1, drug efflux and side-population positive and decreased BCL2-family member expression
(2017-12-06)
Chemotherapeutic drug treatment can result in the emergence of drug-resistant cells. By culturing an interleukin-3 (IL-3)-dependent cell line, FL5.12 cells in the presence of the chemotherapeutic drug doxorubicin, we ...
Health effects following subacute exposure to geogenic dust collected from active drainage surfaces (Nellis Dunes Recreation Area, Las Vegas, NV)
(2017-01)
The specific health effects of direct inhalation of fine minerogenic dusts generated by natural soil surfaces remain poorly known and relatively little researched. To learn more about this exposure and its contri- bution ...
Covariates of Identified Stress and Depression among Seasonal Farmworkers
(2017-06-30)
Many noted difficulties of farmworker life result in increased risk for stress and depression. To date, limited research has focused primarily on seasonal farmworkers; much of the prior research examines migrant farmworkers ...
EphrinA1-Fc attenuates myocardial ischemia/ reperfusion injury in mice
(2017-12-13)
EphrinA1, a membrane-bound receptor tyrosine kinase ligand expressed in healthy car- diomyocytes, is lost in injured cells following myocardial infarction. Previously, we have reported that a single intramyocardial injection ...
Functional imaging of cognition in an old-old population: A case for portable functional near-infrared spectroscopy
(2017-10-12)
In this study, functional near-infrared spectroscopy (fNIRS) was used to record brain activa- tion during cognitive testing in older individuals (88±6yo; N = 19) living in residential care communities. This population, ...
Gemella Species Bacteremia and Stroke in an Elderly Patient with Respiratory Tract Infection
(2017-01-02)
Gemella species are part of normal human flora. They are rarely associated with infections. As opportunistic pathogens, they can cause life-threatening infection in individuals with risk factors. We present an unusual case ...