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Therapeutic targeting of CK2 in acute and chronic leukemias
(2018-01)
Phosphorylation can regulate almost every property of a protein and is involved in all fundamental cellular processes. Thus, proper regulation of phosphorylation events is critical to the homeostatic functions of cell ...
TNM cancer staging: can it help develop a novel staging system for type 2 diabetes?
(2018-11-28)
Abstract: Type 2 diabetes (DM2) constitutes 90%–95% of the diabetes cases and is increasing at an alarming rate in the world. The Centers for Disease Control and Prevention (CDC) esti- mates that more than 29 million people ...
Variation in female aggression in 2 three-spined stickleback populations with female throat and spine coloration
(2018-03-07)
Despite growing interest in female ornament evolution, we still have a rudimentary understanding of female display traits relative to similar traits in males. Under one popular adaptive scenario, fe- male ornaments are ...
The Plight of the Minority Resident Physician— Similar Challenges in a Different World
(2018-09-28)
In the article “Minority Resident Physicians’ Views on the Role of Race/Ethnicity in Their Training Experiences in the Workplace,” Osseo-Asare et al1 report a qualitative approach to teasing out the plight of underrepresented ...
What factors influence older people’s intention to enrol in nursing homes? A cross-sectional observational study in Shanghai, China
(2018-09-05)
Objectives Given the increasing need of long-term care and the low occupancy rate of nursing homes in Shanghai, this study attempts to explore what factors influence older people’s intention to enrol in nursing homes.
Design ...
Position Paper From the Association of Pathology Chairs: Surgical Pathology Residency Training
(2018-12-10)
Training in surgical pathology specimen dissection and microscopic diagnosis is an integral part of pathology residency training, as surgical pathology is one of the defining activities of most pathologists. The Accreditation ...
Position Paper From the Association of Pathology Chairs: Assessing Autopsy Competency in Pathology Residency Training
(2018-12-10)
Declining numbers of hospital autopsies performed in US pathology residency training programs and perceived declining practice of autopsy by many pathologists has caused stakeholder organizations to reassess the role of ...
Premature Ovarian Insufficiency: Procreative Management and Preventive Strategies
(2018-12-28)
Premature ovarian insufficiency (POI) is the loss of normal hormonal and reproductive function of ovaries in women before age 40 as the result of premature depletion of oocytes. The incidence of POI increases with age in ...
MPK-1/ERK is required for the full activity of resveratrol in extended lifespan and reproduction.
(2018-12-21)
Resveratrol (RSV) extends the lifespan of various organisms through activation of sirtuin. However, whether RSV-mediated longevity is entirely dependent upon sirtuin is still controversial. Thus, understanding additional ...
Specialized High‐Protein Oral Nutrition Supplement Improves Home Nutrient Intake of Malnourished Older Adults Without Decreasing Usual Food Intake
(2018-11-22)
Background: Reduced nutrient intake is common in patients after hospitalization, contributing to increased risk for readmissionand mortality. Oral nutrition supplements can improve nutrition status and clinical outcomes, ...