Search
Now showing items 91-100 of 150
Autopsy Standardized Mortality Review: A Pilot Study Offering a Methodology for Improved Patient Outcomes
(2019-02-12)
A standardized mortality review of hospital autopsies identified discrepancies between clinical diagnoses and autopsy findings, unexpected deaths, adequacy of diagnostic workup, presence of adverse event, and type of a ...
Effects of Stathmin 1 Gene Knockout on Behaviors and Dopaminergic Markers in Mice Exposed to Social Defeat Stress
(2019-08-26)
Stathmin (STMN), a microtubule-destabilizing factor, can regulate fear, anxiety, and learning. Social defeat stress (SDS) has detrimental effects on mental health and increases the risk of various psychiatric diseases. ...
Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein
(2019-08-08)
The C-terminal binding protein (CtBP) is an NADH-dependent dimeric family of nuclear proteins that scaffold interactions between transcriptional regulators and chromatin-modifying complexes. Its association with poor ...
Esophageal perforation secondary to malignant gastric outlet obstruction: a case report
(2019-02-19)
Background
Esophageal perforation is a rare presenting sign of gastric cancer. To date, only nine case reports of this phenomenon have been previously published.
Case presentation
Esophageal perforation was diagnosed ...
A system‐based intervention to reduce Black‐White disparities in the treatment of early stage lung cancer: A pragmatic trial at five cancer centers
(2019-01-11)
Background: Advances in early diagnosis and curative treatment have reduced high
mortality rates associated with non‐small cell lung cancer. However, racial disparity
in survival persists partly because Black patients ...
A Waterfront View of Coastal Hazards: Contextualizing Relationships among Geographic Exposure, Shoreline Type, and Hazard Concerns among Coastal Residents
(2019-11-26)
Coastal communities exist on the front lines of diverse natural hazards and the growing
impacts of climate change. While traditional strategies for dealing with coastal hazards have often
involved the hardening or armoring ...
Antivenom Treatment Is Associated with Fewer Patients using Opioids after Copperhead Envenomation
(2019-03-20)
Introduction
Copperhead envenomation causes local tissue destruction, leading people to seek treatment for the pain and swelling. First-line treatment for the pain is opioid medications. There is rising concern that an ...
Abnormal Involuntary Movement Scale in Tardive Dyskinesia:Minimal Clinically Important Difference
(2019-05-27)
Background
A minimal clinically important difference has not been established for the Abnormal Involuntary Movement Scale in patients with tardive dyskinesia. Valbenazine is a vesicular monoamine transporter 2 inhibitor ...
Association of Lowering Low‐Density Lipoprotein Cholesterol With Contemporary Lipid‐Lowering Therapies and Risk of Diabetes Mellitus: A Systematic Review and Meta‐Analysis
(2019-04-02)
Background
The relationship between lowering LDL (low‐density lipoprotein) cholesterol with contemporary lipid‐lowering therapies and incident diabetes mellitus (DM) remains uncertain.
Methods and Results
Thirty‐three ...
Association Between Health Literacy, Electronic Health Literacy, Disease-Specific Knowledge, and Health-Related Quality of Life Among Adults With Chronic Obstructive Pulmonary Disease: Cross-Sectional Study
(2019-06-06)
Background: Despite the relatively high prevalence of low health literacy among individuals living with chronic obstructive pulmonary disease (COPD), limited empirical attention has been paid to the cognitive and health ...