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Drosophila Ctf4 is essential for efficient DNA replication and normal cell cycle progression
(2011-04-06)
Proper coordination of the functions at the DNA replication fork is vital to the normal functioning of a cell. Specifically the precise coordination of helicase and polymerase activity is crucial for efficient passage ...
Executive summary: "Mantle Frontier" workshop
(2011-03)
The workshop on “Reaching the Mantle Frontier: Moho and Beyond” was held at the Broad Branch Road Campus of the Carnegie Institution of Washington on 9–11 September 2010. The workshop attracted seventy-four scientists and ...
Environmental risk factors for autism
(2011)
Autism is a devastating childhood condition that has emerged as an increasing social concern just as it has increased in prevalence in recent decades. Autism and the broader category of autism spectrum disorders are among ...
Estimating internal consistency using Bayesian methods
(2011)
Bayesian internal consistency and its Bayesian credible interval (BCI) are developed and Bayesian internal consistency and its percentile and normal theory based BCIs were investigated in a simulation study. Results indicate ...
How many steps/day are enough? For older adults and special populations
(2011-07-28)
Older adults and special populations (living with disability and/or chronic illness that may limit mobility and/or physical endurance) can benefit from practicing a more physically active lifestyle, typically by increasing ...
Is the genetic landscape of the deep subsurface biosphere affected by viruses?
(2011-11-09)
Viruses are powerful manipulators of microbial diversity, biogeochemistry, and evolution in the marine environment. Viruses can directly influence the genetic capabilities and the fitness of their hosts through the use of ...
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy
(2011-07-01)
Elucidating the response of breast cancer cells to chemotherapeutic and hormonal based drugs is clearly important as these are frequently used therapeutic approaches. A signaling pathway often involved in chemo- and ...
HIV screening and awareness survey for pregnant women in a remote area in Xinjiang Uyghur autonomous region of China
(2011-11-30)
The number of people infected with human immunodeficiency virus (HIV) in China has increased in recent years. HIV screening for pregnant women was performed in a remote area in Xinjiang, as an effort to promote universal ...
PP1 forms an active complex with TLRR (lrrc67), a putative PP1 regulatory subunit, during the early stages of spermiogenesis in mice
(2011-06)
Mammalian spermatogenesis is a highly regulated developmental pathway that demands dramatic rearrangement of the cytoskeleton of the male germ cell. We have described previously a leucine rich repeat protein, TLRR (also ...