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The scale and evolutionary significance of horizontal gene transfer in the choanoflagellate Monosiga brevicollis
(2013-10)
It is generally agreed that horizontal gene transfer (HGT) is common in phagotrophic protists. However, the overall scale of HGT and the cumulative impact of acquired genes on the evolution of these organisms remain largely ...
The Transcriptional Regulator Np20 Is the Zinc Uptake Regulator in Pseudomonas aeruginosa
(2013-09-23)
Zinc is essential for all bacteria, but excess amounts of the metal can have toxic effects. To address this, bacteria have developed tightly regulated zinc uptake systems, such as the ZnuABC zinc transporter which is ...
The role of PPARγ in carbon nanotube-elicited granulomatous lung inflammation
(2013-01-23)
Background
Although granulomatous inflammation is a central feature of many disease processes, cellular mechanisms of granuloma formation and persistence are poorly understood. Carbon nanoparticles, which can be products ...
The effect of race and chronic obstructive pulmonary disease on long-term survival after coronary artery bypass grafting
(2013-04)
Background: Chronic obstructive pulmonary disease (COPD) is a known predictor of decreased long-term survival after coronary artery bypass grafting (CABG). Differences in survival by race have not been examined.
Methods: ...