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The facial inversion effect throughout healthy adult aging : an event-related brain potential study

dc.access.optionOpen Access
dc.contributor.advisorKim, Sunghan, 1975-
dc.contributor.authorWilliams, Patrick M
dc.contributor.departmentEngineering
dc.date.accessioned2019-08-21T18:51:09Z
dc.date.available2019-08-21T18:51:09Z
dc.date.created2019-08
dc.date.issued2019-07-02
dc.date.submittedAugust 2019
dc.date.updated2019-08-19T17:40:45Z
dc.degree.departmentEngineering
dc.degree.disciplineMS-Biomedical Engineering
dc.degree.grantorEast Carolina University
dc.degree.levelMasters
dc.degree.nameM.S.
dc.description.abstractAge-associated cognitive decline (AACD) is a natural part of life. The difference between malignant and benign AACD can be difficult to determine in the early stages of dementia. Many factors affect an individual's brain changes throughout their life; therefore, the detection of dementia commonly requires longitudinal studies. By the time the symptoms of dementia manifest the damage to one's central nervous system is irreversible. The investigation of biomarkers for the early detection of dementia is ongoing. Electroencephalogram (EEG) research, along with other neuroimaging and clinical testing, has shown that it is possible to detect subtle changes to the central nervous system before the onset of behavioral changes due to dementia. In this research, a sequential imaging oddball paradigm that utilizes upright and inverted familiar and unfamiliar faces were used to scrutinize the effect of facial inversion throughout healthy adult aging. The results indicate that late event-related potentials such as the P300 and late positive potential may be biomarkers for the tracking of age-related changes. Additionally, it may be concluded that the oddball paradigm is not the optimal way to elicit the face inversion effect. Further research is recommended in order to develop conclusions which could not be determined due to limited population and sample size.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttp://hdl.handle.net/10342/7446
dc.language.isoen
dc.publisherEast Carolina University
dc.subjectMild Cognitive Impairment
dc.subjectAlzheimer's Disease
dc.subjectProcessing
dc.subjectSpectral
dc.subjectAnalysis
dc.subjectBiomarker
dc.subjectOddball
dc.subjectP300
dc.subjectN170
dc.subjectN400
dc.subjectP600
dc.subjectLate Positive Potential
dc.subjectFieldtrip
dc.subjectMATLAB
dc.subject.lcshCognition disorders in old age
dc.subject.lcshElectroencephalography--Age factors
dc.subject.lcshDementia--Etiology
dc.titleThe facial inversion effect throughout healthy adult aging : an event-related brain potential study
dc.typeMaster's Thesis
dc.type.materialtext

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