HOW CAN WE REDUCE THE EFFECTS OF ENVIRONMENTAL POLLUTANTS ON THE PLACENTA?

dc.access.optionOpen Access
dc.contributor.advisorMcCoy, Krista
dc.contributor.authorFricke, Ariel
dc.contributor.departmentBiology
dc.date.accessioned2021-01-04T17:12:42Z
dc.date.available2022-12-01T09:02:00Z
dc.date.created2020-12
dc.date.issued2020-11-19
dc.date.submittedDecember 2020
dc.date.updated2020-12-18T14:31:32Z
dc.degree.departmentBiology
dc.degree.disciplineMS-Biology
dc.degree.grantorEast Carolina University
dc.degree.levelMasters
dc.degree.nameM.S.
dc.description.abstractPrenatal exposure to endocrine disrupting chemicals can lead to birth defects and adult disease. While it is impossible to avoid pollutant exposure, development of a prenatal supplement that augments natural protective mechanisms would be invaluable. Here, I show that prenatal supplementation with sulforaphane reduces gene changes caused by a model endocrine disrupting chemical. Further the candidate mechanisms of resilience associated with this rescue were identified.
dc.embargo.lift2022-12-01
dc.format.mimetypeapplication/pdf
dc.identifier.urihttp://hdl.handle.net/10342/8822
dc.language.isoen
dc.publisherEast Carolina University
dc.subjectNrf2
dc.subjectSulforaphane
dc.subjectPrenatal Development
dc.subject.lcshEndocrine disrupting chemicals--Health aspects
dc.subject.lcshAbnormalities, Human
dc.subject.lcshEnvironmental health
dc.subject.lcshPollutants
dc.titleHOW CAN WE REDUCE THE EFFECTS OF ENVIRONMENTAL POLLUTANTS ON THE PLACENTA?
dc.typeMaster's Thesis
dc.type.materialtext

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