HOW CAN WE REDUCE THE EFFECTS OF ENVIRONMENTAL POLLUTANTS ON THE PLACENTA?
dc.access.option | Open Access | |
dc.contributor.advisor | McCoy, Krista | |
dc.contributor.author | Fricke, Ariel | |
dc.contributor.department | Biology | |
dc.date.accessioned | 2021-01-04T17:12:42Z | |
dc.date.available | 2022-12-01T09:02:00Z | |
dc.date.created | 2020-12 | |
dc.date.issued | 2020-11-19 | |
dc.date.submitted | December 2020 | |
dc.date.updated | 2020-12-18T14:31:32Z | |
dc.degree.department | Biology | |
dc.degree.discipline | MS-Biology | |
dc.degree.grantor | East Carolina University | |
dc.degree.level | Masters | |
dc.degree.name | M.S. | |
dc.description.abstract | Prenatal exposure to endocrine disrupting chemicals can lead to birth defects and adult disease. While it is impossible to avoid pollutant exposure, development of a prenatal supplement that augments natural protective mechanisms would be invaluable. Here, I show that prenatal supplementation with sulforaphane reduces gene changes caused by a model endocrine disrupting chemical. Further the candidate mechanisms of resilience associated with this rescue were identified. | |
dc.embargo.lift | 2022-12-01 | |
dc.format.mimetype | application/pdf | |
dc.identifier.uri | http://hdl.handle.net/10342/8822 | |
dc.language.iso | en | |
dc.publisher | East Carolina University | |
dc.subject | Nrf2 | |
dc.subject | Sulforaphane | |
dc.subject | Prenatal Development | |
dc.subject.lcsh | Endocrine disrupting chemicals--Health aspects | |
dc.subject.lcsh | Abnormalities, Human | |
dc.subject.lcsh | Environmental health | |
dc.subject.lcsh | Pollutants | |
dc.title | HOW CAN WE REDUCE THE EFFECTS OF ENVIRONMENTAL POLLUTANTS ON THE PLACENTA? | |
dc.type | Master's Thesis | |
dc.type.material | text |
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