Browsing by Author "Feng, Yuanming"
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Assessment of single-spot TOPAS MC simulation for proton pencil beam scanning in homogeneous and heterogeneous media and quantification of dosimetric impact of CT metal artifact on IMPT and VMAT plans
Lin, Chun-I (East Carolina University, 2020-11-17)Proton pencil beam scanning (PBS) radiation therapy has become thriving worldwide. The accuracy of proton dose calculation that based on proper modeling for each single scanning spot as well as accurate CT image data is ... -
Automatic quantitative analysis of morphology of apoptotic HL-60 cells
Liu, Yahui; Lin, Wang; Yang, Xu; Liang, Weizi; Zhang, Jun; Meng, Maobin; Rice, John R.; Sa, Yu; Feng, Yuanming (2014-01)Morphological identification is a widespread procedure to assess the presence of apoptosis by visual inspection of the morphological characteristics or the fluorescence images. The procedure is lengthy and results are ... -
Diffusion and perfusion weighted magnetic resonance imaging for tumor volume definition in radiotherapy of brain tumors
Guo, Lu; Wang, Gang; Feng, Yuanming; Yu, Tonggang; Guo, Yu; Bai, Xu; Ye, Zhaoxiang (2016-09-21)Abstract Accurate target volume delineation is crucial for the radiotherapy of tumors. Diffusion and perfusion magnetic resonance imaging (MRI) can provide functional information about brain tumors, and they ... -
Diffusion and perfusion weighted magnetic resonance imaging for tumor volume definition in radiotherapy of brain tumors
Guo, Lu; Wang, Gang; Feng, Yuanming; Yu, Tonggang; Guo, Yu; Bai, Xu; Ye, Zhaoxiang (2016-09-21)Accurate target volume delineation is crucial for the radiotherapy of tumors. Diffusion and perfusion magnetic resonance imaging (MRI) can provide functional information about brain tumors, and they are able to detect tumor ... -
Evaluation of Magnetic Resonance Imaging in Prostate Radiotherapy for Improved Treatment Outcomes
Ruiz, Brian (East Carolina University, 2019-05-01)External beam radiation therapy is among the most common modalities of curative treatment for prostate cancer and has evolved substantially with the inclusion of multimodality imaging in treatment planning. It has been ... -
An Expanded Multi-scale Monte Carlo Simulation Method for Personalized Radiobiological Effect Estimation in Radiotherapy: a feasibility study
Zhang, Ying; Feng, Yuanming; Wang, Wei; Yang, Chengwen; Wang, Ping (2017-03-21)A novel and versatile “bottom-up” approach is developed to estimate the radiobiological effect of clinic radiotherapy. The model consists of multi-scale Monte Carlo simulations from organ to cell levels. At cellular level, ... -
Feasibility Study of Dual Energy Radiographic Imaging for Target Localization in Radiotherapy for Lung Tumors
Huo, Jie; Zhu, Xianfeng; Dong, Yang; Yuan, Zhiyong; Wang, Ping; Wang, Xuemin; Wang, Gang; Hu, Xin-Hua; Feng, Yuanming (2014)Purpose Dual-energy (DE) radiographic imaging improves tissue discrimination by separating soft from hard tissues in the acquired images. This study was to establish a mathematic model of DE imaging based on intrinsic ... -
A fuzzy feature fusion method for auto-segmentation of gliomas with multi-modality diffusion and perfusion magnetic resonance images in radiotherapy
Guo, Lu; Wang, Ping; Sun, Ranran; Yang, Chengwen; Zhang, Ning; Guo, Yu; Feng, Yuanming (2018-02-19)The difusion and perfusion magnetic resonance (MR) images can provide functional information about tumour and enable more sensitive detection of the tumour extent. We aimed to develop a fuzzy feature fusion method for ... -
Label-free classification of cultured cells through diffraction imaging
Dong, Ke; Feng, Yuanming; Jacobs, Kenneth M.; Lu, Jun Q.; Brock, R. Scott; Yang, Li V.; Bertrand, Fred E.; Farwell, Mary A.; Hu, Xin-Hua (2011-05)Automated classification of biological cells according to their 3D morphology is highly desired in a flow cytometer setting. We have investigated this possibility experimentally and numerically using a diffraction imaging ... -
A Mathematical Model of Tumor Volume Changes during Radiotherapy
Wang, Ping; Feng, Yuanming (2013)Purpose. To develop a clinically viable mathematical model that quantitatively predicts tumor volume change during radiotherapy in order to provide treatment response assessment for prognosis, treatment plan optimization, ... -
A new assessment model for tumor heterogeneity analysis with [18]F-FDG PET images
Wang, Ping; Xu, Wengui; Sun, Jian; Yang, Chengwen; Wang, Gang; Sa, Yu; Hu, Xin-Hua; Feng, Yuanming (2016-01)It has been shown that the intratumor heterogeneity can be characterized with quantitative analysis of the [18]F-FDG PET image data. The existing models employ multiple parameters for feature extraction which makes it ... -
PROFILING EFFUSION CELLS BY QUANTITATIVE ANALYSIS OF MORPHOLOGY AND DIFFRACTION IMAGING PATTERNS
Al-Qaysi, Safaa (East Carolina University, 2019-04-12)Profiling cells in human pleural and peritoneal effusion (PPE) samples is an essential task for cytological diagnosis of cancers and patient management. Conventional PPE cytology of a PPE sample is labor intensive and its ... -
Quantitative assessment of image motion blur in diffraction images of moving biological cells
Wang, He; Jin, Changrong; Feng, Yuanming; Qi, Dandan; Sa, Yu; Hu, Xin-Hua (2016-02)Motion blur (MB) presents a significant challenge for obtaining high-contrast image data from biological cells with a polarization diffraction imaging flow cytometry (p-DIFC) method. A new p-DIFC experimental system has ... -
A Tri-Modality Image Fusion Method for Target Delineation of Brain Tumors in Radiotherapy
Guo, Lu; Shen, Shuming; Harris, Eleanor; Wang, Zheng; Jiang, Wei; Guo, Yu; Feng, Yuanming (2014)Purpose To develop a tri-modality image fusion method for better target delineation in image-guided radiotherapy for patients with brain tumors. Methods A new method of tri-modality image fusion was developed, ...