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Orphan Glutamate Receptor delta-1 Subunit Required for High-Frequency Hearing
(East Carolina University, 2007-06)
The function of the orphan glutamate receptor delta subunits (GluR 1 and GluR 2) remains unclear. GluR 2 is expressed exclusively in the Purkinje cells of the cerebellum, and GluR 1 is prominently expressed in inner ear ...
A Quantitative Survey of Gravity Receptor Function in Mutant Mouse Strains
(East Carolina University, 2005-12)
The purpose of this research was to identify vestibular deficits in mice using linear vestibular evoked potentials (VsEPs). VsEP thresholds, peak latencies, and peak amplitudes from 24 strains with known genetic mutations ...
Functional Aging of the Inner Ear Sensory Systems in Mouse Models of Age-Related Hearing Loss
(East Carolina University, 2009)
Age related structural and functional change in the cochlea have been well described and predisposing factors including genetic background, gender, and environmental factors have been identified. To date, nine genetic loci ...
Methods and devices for treating stuttering problems
(2000-12-18)
Methods, devices, and computer program products display visual choral speech to a patient who stutters or has a speech impediment or impairment as a visual stimulus for the patient to enhance the fluency of the patient. ...
An Investigation of Auditory and Visual Temporal Processing in Children with Reading Disorders
(East Carolina University, 2009)
Several lines of research have revealed a relationship between reading disorders (RD) and auditory temporal processing deficits. That is, subtle, yet rapid changes within an acoustic message are more difficult for individuals ...
Spontaneous Discharge Patterns in Cochlear Spiral Ganglion Cells Prior to the Onset of Hearing in Cats
(East Carolina University, 2007-10)
Spontaneous neural activity has been recorded in the auditory nerve of cats as early as 2 days postnatal (P2 ), yet individual auditory neurons do not respond to ambient sound levels below 90–100 dB SPL until about P10. ...
Resting Discharge Patterns of Macular Primary Afferents in Otoconia-Deficient Mice
(East Carolina University, 2008-12)
Vestibular primary afferents in the normal mammal are spontaneously active. The consensus hypothesis states that such discharge patterns are independent of stimulation and depend instead on excitation by vestibular hair ...
Osteopontin is not Critical for Otoconia Formation or Balance Function
(East Carolina University, 2008-06)
Unlike the structural and mechanical role of bone crystals, the inertial mass of otoconia crystals provides a shearing force to stimulate the mechanoreceptors of the utricle and saccule (the gravity receptor organ)under ...
Implementation Of An In-The-Ear Device To Alleviate Stuttering: Research Evidence
(East Carolina University, 2006)
Methods and devices for delivering exogenously generated speech signals to enhance fluency in persons who stutter
(2004-06-22)
Methods and devices generate an exogenous natural second speech signal as an auditory stimulus to a user to enhance the fluency of persons who stutter. The natural speech signal is independent of the contemporaneous speech ...