Browsing Dissertations by Title
Now showing items 251-270 of 1044
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Development of Computational Tools and Resources for Cotton microRNA Analysis
(East Carolina University, 2014)MicroRNAs (miRNAs) are an extensive class of small regulatory RNAs which regulate gene expression at the posttranscriptional levels. miRNAs target genes for mRNA cleavage or translation inhibition based on the complementary ... -
Development of Green Subcritical Water Separation Technology
(East Carolina University, 2019-08-19)Theoretically speaking, water under temperature and pressure conditions below its critical point is called subcritical water. However, the term “subcritical water” normally refers to hot water up to 374 C and pressure up ... -
Development of the Peripartum Cardiomyopathy Quality Of Life Registry
(East Carolina University, 2016-07-08)Peripartum cardiomyopathy (PPCM) is a relatively rare form of heart failure that develops in young women in the third trimester of pregnancy or during the postpartum period. Despite its potentially devastating impact on ... -
DIFFERENCES IN ACCESS AND QUALITY OF CARE DURING ACUTE ISCHEMIC STROKE: FINDINGS FROM THE REGARDS STUDY
(East Carolina University, 2022-04-25)Evidence suggests there are discrepancies in access and quality of care during hospitalization for acute ischemic stroke. The aim of this study was to characterize differences in receipt of neurologist evaluation, documented ... -
Direct Behavior Ratings (DBR) : A possible tool for monitoring the behavior and interventions of students with symptoms of Attention Deficit Hyperactivity Disorder (ADHD)
(East Carolina University, 2011)Considering the time constrains of school teachers it is imperative to identify more time efficient procedures to monitor behavior and interventions for students exhibiting symptoms of Attention Deficit Hyperactivity ... -
Discourse Process Training and Attention Process Training 2 in Adults with Traumatic Brain Injury
(East Carolina University, 2019-05-01)Persons with traumatic brain injury (TBI) often present with relatively preserved lexical and grammatical skills but exhibit discourse level deficits which negatively affect functional communication. Discourse following ... -
Discourse Processing in Neurologically Healthy Adults: A Cross-Modal Eye tracking Study
(East Carolina University, 2021-07-20)One of the methods to study discourse comprehension is inference revision. Inferencing can be defined as a controlled, information-generation process that requires deductive reasoning abilities (Kintsch, 1998). Studies ... -
Discovering mechanisms during spermatogonial differentiation that prepare male germ cells for meiosis
(East Carolina University, 2022-12-05)Spermatogenesis, the male germ cell maturation process, allows men to become and remain fertile for decades. Male fertility relies on fate decisions of different types of spermatogonia – spermatogonial stem cells maintain ... -
Discovery and investigation of a novel role for mitochondrial prohibitin in mitigating acute heart failure in endotoxic shock
(East Carolina University, 2014)Sepsis results in more than 200,000 deaths annually and is the 10th leading cause of death in the United States (US). In spite of significant advances in medical care the mortality rate for sepsis has continued to rise. ... -
DISCRIMINATING BETWEEN CARDIOLIPIN CONCENTRATION AND ACYL CHAIN COMPOSITION ON MEMBRANE BIOPHYSICAL ORGANIZATION
(East Carolina University, 2018-11-28)The pathogenesis of cardiovascular diseases (CVDs) is driven, in part, from impairment in myocardial energy metabolism. There is convincing evidence that myocardial metabolic abnormalities are fundamentally driven by ... -
Disrupted Adiponectin-Connexin43 Signaling Underlies Exacerbated Myocardial Dysfunction in Diabetic Female Rats
(East Carolina University, 2019-04-25)The 2015 American Heart Association scientific statement has advocated for sex- specific research to understand the paradoxically higher sensitivity of women to type 2 diabetes mellitus (T2DM)-associated cardiovascular ... -
Disruption of mitochondrial fitness in human preadipocytes by fatty acids
(East Carolina University, 2013)Adipose tissue lies at the core of energy metabolism, by not only releasing and taking up fatty acids (FA) according to the individuals overall surplus or deficit of energy, but also signaling other tissues to regulate ... -
Distance Education Leaders' Perspectives: A Study of How Select Higher Education Institutions Implement and Lead Online Distance Education Programs
(East Carolina University, 2008-04-09)The purpose of this research was to study the perspectives, characteristics, and experiences of ten distance education leaders at four-year, not-for-profit, degree-granting higher education institutions implementing online ... -
The Distribution Of Regulated Actomyosin States Is Central To Cardiac Muscle Regulation And Disturbance Of This Distribution Leads To Congenital Cardiomyopathies
(East Carolina University, 2009)Hypertrophic and restrictive cardiomyopathies are congenital cardiac diseases that have an incidence of over one in five hundred and may lead to sudden cardiac death. One of the main impediments to directed treatment is ... -
Diversity and Survival of Macrofauna associated with a Non-Native Foundational Species
(East Carolina University, 2023-07-24)Through globalization and increased anthropogenic movement, many non-native foundation species have established across the world. These foundation species have impacted ecological communities in myriad of ways, including ... -
Division I Athletics Directors and University Presidents : A Comparison of Sport-Related Values
(East Carolina University, 2008)The purpose of this study was to analyze the moral reasoning of university presidents and athletics directors in sport settings, an area into which few initiatives have been undertaken. Electronic surveys were used to ... -
Docosahexaenoic acid-derived metabolites target the B-cell driven immune response in obese mice
(East Carolina University, 2019-06-07)Obesity is associated with an impaired humoral immune response. As B cells mediate the humoral immune response, they are major cellular targets in diet induced obesity models. Several studies have established that B cell ... -
DOES THE DELIVERY METHOD OF FIRST-YEAR EXPERIENCE COURSES AFFECT STUDENT SUCCESS?
(East Carolina University, 2023-06-22)As state budgets are continuously tightened, and state dollars dwindle to cover only the bare necessities, resources must be carefully examined and utilized to increase efficiency and effectiveness; one such area in which ... -
DOSIMETRIC STUDY OF BETA-MINUS EMITTER PRASEODYMIUM-142 : APPLICATIONS IN MICROSPHERE BRACHYTHERAPY FOR HEPATOCELLULAR CARCINOMA AND BRACHYTHERAPY FOR OCULAR SQUAMOUS CELL CARCINOMA
(East Carolina University, 2013)A dosimetric study of the beta-minus emitter Praseodymium-142 (¹⁴²Pr) was performed and two main innovative applications of this source in brachytherapy are proposed: microsphere brachytherapy and eye plaque brachytherapy. ... -
DUAL LANGUAGE LEARNING: USING FIRST LANGUAGE AS A SCAFFOLD FOR SECOND LANGUAGE ACQUISITION AND LEARNING
(East Carolina University, 2021-04-20)For most English language learners, translanguaging strategies applied in a fully inclusive classroom are most effective for acquiring second-language competency. However, teachers of non-language subjects such as math and ...