Browsing Dissertations by Author "Fisher-Wellman, Kelsey"
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Skeletal Muscle Purine Nucleotide Degradation and Atrophy: Cause or Consequence of Increased Uric Acid Production
Miller, Spencer Graham (East Carolina University, 2022-07-26)Elevated serum uric acid is a risk factor for mortality in diseases and critical illnesses associated with skeletal muscle atrophy. Uric acid is generated by xanthine oxidoreductase (XOR) and XOR inhibitors can partially ...