Browsing Dissertations by Subject "Vaccines"
Now showing items 1-3 of 3
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Evaluation of the use of Wastewater Based Epidemiology as a Surveillance Tool and the Potential effects of Vaccines and Students Beliefs and Practices in Mitigating the Spread of COVID-19 Among Students at East Carolina University
(East Carolina University, 2022-12-01)Worldwide, newly emerging and re-emerging infectious diseases and pathogens have led to increases in the number and frequency of disease outbreaks. Although these disease outbreaks are not new, increases in outbreaks have ... -
Experimental autoimmune encephalomyelitis as a model of Multiple Sclerosis : pathogenesis of atypical disease and tolerance induction in chronic progressive disease
(East Carolina University, 2015)Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) of putative autoimmune origin characterized by focal inflammatory lesions together with demyelinating plaques in the ... -
A SINGLE-CHAIN GMCSF-MOG TOLEROGENIC VACCINE EXPANDS MOG-SPECIFIC CD25+ FOXP3+ REGULATORY T CELLS THROUGH LOW-EFFICIENCY ANTIGEN RECOGNITION EVENTS TO INHIBIT EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
(2019-12)Previous studies showed that tolerogenic vaccines comprised of single-chain GMCSF-neuroantigen (NAg) fusion proteins inhibited experimental autoimmune encephalomyelitis (EAE) in rodents. The studies detailed here provide ...