Browsing Microbiology and Immunology by Author "McKnight, Susan L."

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  • Functions Required for Extracellular Quinolone Signaling by Pseudomonas aeruginosa 

    Gallagher, Larry A.; McKnight, Susan L.; Kuznetsova, Marina S.; Pesci, Everett C.; Manoil, Colin (East Carolina University, 2002-12)
    A set of 30 mutants exhibiting reduced production of the phenazine poison pyocyanin were isolated following transposon mutagenesis of Pseudomonas aeruginosa PAO1. The mutants could be subdivided into those with defects in ...

  • Pseudomonas aeruginosa PqsA Is an Anthranilate-Coenzyme A Ligase 

    Coleman, James P.; Hudson, L. Lynn; McKnight, Susan L.; Farrow, John M. III; Calfee, M. Worth; Lindsey, Claire A.; Pesci, Everett C. (East Carolina University, 2008-02)
    Pseudomonas aeruginosa is an opportunistic human pathogen which relies on several intercellular signaling systems for optimum population density-dependent regulation of virulence genes. The Pseudomonas quinolone signal ...

  • The Pseudomonas Quinolone Signal Regulates rhl Quorum Sensing in Pseudomonas aeruginosa 

    McKnight, Susan L.; Iglewski, Barbara H.; Pesci, Everett C. (East Carolina University, 2000-05)
    The opportunistic pathogen Pseudomonas aeruginosa uses intercellular signals to control the density-dependent expression of many virulence factors. The las and rhl quorum-sensing systems function, respectively, through the ...

  • Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa 

    Pesci, Everett C.; Milbank, Jared B. J.; Pearson, James P.; McKnight, Susan L.; Kende, Andrew S.; Greenberg, E. Peter; Iglewski, Barbara H. (East Carolina University, 1999-09-28)
    Numerous species of bacteria use an elegant regulatory mechanism known as quorum sensing to control the expression of specific genes in a cell-density dependent manner. In Gram-negative bacteria, quorum sensing ...