Browsing Microbiology and Immunology by Author "Whelan, Jarrett Thomas"
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Enforced expression of HoxA9 in b-lineage all promotes survival and proliferation of leukemic cells
Whelan, Jarrett Thomas (East Carolina University, 2009)HoxA9 is frequently overexpressed in acute myeloid leukemia, myelodysplastic syndrome and a subset of acute lymphoblastic leukemia. In mouse models, HoxA9 has been shown to promote leukemogenesis. In spite of a seemingly ... -
Hox-gene expression as a biomarker for igf-1r therapeutics
Bertrand, Fred E.; Whelan, Jarrett Thomas (2008-09-25)This invention provides methods for treating or preventing the onset of a tumor in a subject, wherein the tumor is determined to overexpress a Hox gene, including administering to the subject a therapeutically or ...