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Differential regulation of the attachment of KSHV infected human B cells to ECM by KSHV encoded gB and cellular alpha-V integrins
(East Carolina University, 2008-07)
Kaposi’s sarcoma-associated herpesvirus (KSHV) has two modes replication: latent and lytic replication. Reactivation from latency is dictated, in part, by the cell cycle. Herein, we have attempted to delineate the importance ...
Raf-Induced Vascular Endothelial Growth Factor Augments Kaposi's Sarcoma-Associated Herpesvirus Infection
(East Carolina University, 2004-12)
Recombinant green fluorescent protein encoding Kaposi’s sarcoma-associated herpesvirus (rKSHV.152) infection of -estradiol stimulated human foreskin fibroblasts (HFF) or HFF/ B-Raf[FF]:ER (expressing a weaker form of ...
Raman spectroscopy: the gateway into tomorrow's virology
(East Carolina University, 2006-06-28)
In the molecular world, researchers act as detectives working hard to unravel the mysteries surrounding cells. One of the researchers' greatest tools in this endeavor has been Raman spectroscopy. Raman spectroscopy is a ...
Resveratrol Inhibits KSHV Reactivation by Lowering the Levels of Cellular EGR-1
(2012)
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Subcellular fractionation method to study endosomal trafficking of Kaposi’s sarcoma-associated herpesvirus
(2016-01)
Background
Virus entry involves multiple steps and is a highly orchestrated process on which successful infection collectively depends. Entry processes are commonly analyzed by monitoring internalized virus particles ...
KSHV gB associated RGD interactions promote attachment of cells by inhibiting the potential migratory signals induced by the disintegrin-like domain
(2016-02)
Background: Kaposi's sarcoma-associated herpesvirus (KSHV) glycoprotein B (gB) is not only expressed on the envelope of mature virions but also on the surfaces of cells undergoing lytic replication. Among herpesviruses, ...
Raman tweezers provide the fingerprint of cells supporting the late stages of KSHV reactivation
(East Carolina University, 2009-08)
Kaposi's sarcoma-associated herpesvirus (KSHV) has both latent and lytic phases of replication. The molecular switch that triggers a reactivation is still unclear. Cells from S phase of cell cycle provide apt conditions ...
Subcellular fractionation method to study endosomal trafficking of Kaposi’s sarcoma-associated herpesvirus
(2016-01-15)
Background:
Virus entry involves multiple steps and is a highly orchestrated process on which successful infection collectively depends. Entry processes are commonly analyzed by monitoring internalized virus particles ...