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Now showing items 11-16 of 16
SPATIAL EXPRESSION OF MATRIX AND MATRIX RECEPTOR PROTEINS IN THE DEVELOPING SYNOVIAL JOINT
(East Carolina University, 2013)
Little is understood about the complex spatial and temporal molecular interactions necessary to form a fully functional synovial joint. Understanding molecular pathways and signaling within the developing joint continues ...
Selection of Reliable Reference Genes in for Analysis of Nanotoxicity
(2012)
Despite rapid development and application of a wide range of manufactured metal oxide nanoparticles (NPs), the understanding of potential risks of using NPs is less completed, especially at the molecular level. The nematode ...
Deep Sequencing Reveals Transcriptome Re-Programming of Cells to the Elicitation with Methyl Jasmonate
(2013)
Background
Plant cell culture represents an alternative source for producing high-value secondary metabolites including paclitaxel (Taxol®), which is mainly produced in Taxus and has been widely used in cancer chemotherapy. ...
Connecting Mutations of the RNA Polymerase II C-Terminal Domain to Complex Phenotypic Changes Using Combined Gene Expression and Network Analyses
(2010)
The C-terminal domain (CTD) of the largest subunit in DNA-dependent RNA polymerase II (RNAP II) is essential for mRNA synthesis and processing, through coordination of an astounding array of protein-protein interactions. ...
Characterizing the vegetative phenotype of fzt maize mutant
(East Carolina University, 2012)
microRNAs are short, non-coding RNA strands that regulate gene expression post-transcriptionally in all multicellular organisms. miRNAs begin as a hairpin in the nucleus. The primary miRNA (pri-miRNA) and preliminary ...
Effects of Nicotine on Caenorhabditis elegans survival, reproduction, and gene expressions : Development of an Invertebrate Animal Model for Drugs of Abuse
(East Carolina University, 2011)
Although much is known about the addictive effects of nicotine, the molecular mechanisms of nicotine-induced effects remain largely unclear. Specifically, little is known about the effects of nicotine on gene expression, ...