Search
Now showing items 31-40 of 78
ANALYSIS OF OXYGENATED POLYCYCLIC AROMATIC HYDROCARBONS AND THEIR PARENT MOLECULES IN BIOCHAR AND ITS LEACHATES
(East Carolina University, 2017-12-13)
Due to the increasing use of biochar as a soil amendment, the amount and composition of contaminants in biochar should be analyzed. Two of those suites of compounds in biochar are polycyclic aromatic hydrocarbons (PAHs) ...
Benzoate: The Quantitation of Soft Drinks Implicated in Obesity
(East Carolina University, 2019-04-26)
Research has shown that childhood obesity is a leading cause of diseases such as coronary artery disease, hypertension, type 2 diabetes, cancer, osteoarthritis, and many more. With approximately 17 percent of the United ...
Platinum Catalyzed Synthesis of Alpha-Ketoester via C-H Functionalization
(East Carolina University, 2019-12-16)
Alpha-ketoesters have proven to be useful in a variety of fields. They have found wide spread applications in pharmaceuticals, photochemistry, and biology. Additionally, they are of great interest in synthetic chemistry ...
Development of Green Subcritical Water Separation Technology
(East Carolina University, 2019-08-19)
Theoretically speaking, water under temperature and pressure conditions below its critical point is called subcritical water. However, the term “subcritical water” normally refers to hot water up to 374 C and pressure up ...
Theoretical Probe to the Mechanism of Pt-catalyzed C-H Acylation Reaction: Possible Pathways for the Key Acylation Reaction of Platinacycles
(East Carolina University, 2019-08-23)
Transition metal-catalyzed C-H bond functionalization offers a variety of desirable transformations of simple hydrocarbons to more complex compounds with applications being applied in pharmaceuticals to material sciences. ...
protaTETHER – a method for the incorporation of variable linkers in protein fusions reveals impacts of linker flexibility in a PKAc‐GFP fusion protein
(2018-03-14)
Protein fusions are of fundamental importance in the study of cellular biology and the elucidation of cell signaling pathways, and the importance of linkers for the proper function of protein fusions is well documented in ...
Fluorescent Derivatives of Prostamides: Tools for Studying Anti-Cancer Activity
(East Carolina University, 2018-07-23)
The endocannabinoid arachidonoyl ethanolamide (AEA) and prostaglandins derived from it selectively induce apoptosis in tumorigenic cell lines due to overexpression of COX-2. It is likely that a novel J-series prostamide, ...
Counting Protons: Using Isothermal Titration Calorimetry to Determine the Number of Protons Exchanged Upon Ca(II) and Cd(II) Binding to Wild-type HcTnC and Mutant C84A and C35A/C84A Proteins
(East Carolina University, 2018-07-20)
Maintaining a delicate balance of metal ions in the cell is crucial to the survival of many organisms. Divalent cadmium, Cd(II), is a non-essential metal ion that can disrupt this delicate balance and lead to deleterious ...
Using Fluorescence and Infrared Spectroscopy to Analyze the Interaction of Disaccharides with Lipid Bilayers
(East Carolina University, 2018-07-24)
It is well known that sugars, such as trehalose, dehydrate lipid membranes based upon the Water Replacement Hypothesis. Here, we have investigated the interaction between different sugars (sucralose, sucrose, and trehalose) ...
Heavy Metal Concentrations in Biofluid Samples and their Correlation to Metabolic Syndrome
(East Carolina University, 2018-05-01)
The goal of this project was to determine if toxic metals such as Cr, Mn, As, Ni, Cd, and Pb are stored in the adipose tissue of farm animals, in particular swine. To detect these trace elements, a method of extraction and ...