Browsing Physics by Type"Doctoral Dissertation"
Now showing items 1-20 of 24
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A solution method determining the effect of spin upon gravitational effects in the surroundings of a black hole
(East Carolina University, 2017-12-12)Using the theory of General Relativity and quasi-normal modes (QNMs) from the Teukolsky equation as a source of quasi-periodic oscillations (QPOs) from black holes provides information about black hole mass and spin. This ... -
Analysis of Circular Dichroism and Linear Dichroism Spectroscopy
(East Carolina University, 2012)Circular Dichroism (CD) and Linear Dichroism (LD) spectroscopies measure the difference in absorption between left and right circularly polarized light and parallel and perpendicular linearly polarized light as a function ... -
Assessment of single-spot TOPAS MC simulation for proton pencil beam scanning in homogeneous and heterogeneous media and quantification of dosimetric impact of CT metal artifact on IMPT and VMAT plans
(East Carolina University, 2020-11-17)Proton pencil beam scanning (PBS) radiation therapy has become thriving worldwide. The accuracy of proton dose calculation that based on proper modeling for each single scanning spot as well as accurate CT image data is ... -
COMPARATIVE ANALYSIS OF TWO HUMAN CANCER CELL LINES FOLLOWING EXPOSURE TO LOW DOSE RADIATION
(East Carolina University, 2011)Over the past two decades, studies on the cellular response to very low dose radiation have been revolutionizing historically-held paradigms of cellular radioresponse. Indeed, a host of seemingly contradictory events have ... -
COMPARISON OF TWO HUMAN CELL LINES FOLLOWING EXPOSURE TO LOW DOSE RADIATION AND TREATMENT WITH SOYBEAN MISO AND ITS ACTIVE INGREDIENT GENISTEIN
(East Carolina University, 2013)Exposure to radiation is increasingly becoming a worldwide health issue. Because of this, the need for effective radioprotectors is critical. This need is not met by amifostine, the current "gold standard" in radioprotectors, ... -
Correlating the Morphological and Light Scattering Properties of Biological Cells
(East Carolina University, 2013)The scattered light pattern from a biological cell is greatly influenced by the internal structure and optical properties of the cell. This research project examines the relationships between the morphological and scattering ... -
Development of a Diffraction Imaging Flow Cytometer for Study of Biological Cells
(East Carolina University, 2010)Visible light interacts with biological cells primarily through elastic scattering. With coherent excitation the scattered light is coherent as well and contains much information about the cells morphology but with the ... -
DOSIMETRIC STUDY OF BETA-MINUS EMITTER PRASEODYMIUM-142 : APPLICATIONS IN MICROSPHERE BRACHYTHERAPY FOR HEPATOCELLULAR CARCINOMA AND BRACHYTHERAPY FOR OCULAR SQUAMOUS CELL CARCINOMA
(East Carolina University, 2013)A dosimetric study of the beta-minus emitter Praseodymium-142 (¹⁴²Pr) was performed and two main innovative applications of this source in brachytherapy are proposed: microsphere brachytherapy and eye plaque brachytherapy. ... -
Evaluation of Magnetic Resonance Imaging in Prostate Radiotherapy for Improved Treatment Outcomes
(East Carolina University, 2019-05-01)External beam radiation therapy is among the most common modalities of curative treatment for prostate cancer and has evolved substantially with the inclusion of multimodality imaging in treatment planning. It has been ... -
Fast Carbon-Ion and Proton Induced Electron Emission from Condensed-Phase Biological Targets
(East Carolina University, 2018-07-23)Fast charged particles interact with matter through various ionization and excitation pathways that aren't fully understood. Predicting the effects of these interactions is vital in many fields such as radiation therapy, ... -
FETUS PHANTOM CONSTRUCTIONS FOR OVERWEIGHT AND OBESE PREGNANT FEMALES FOR RADIOLOGICAL APPLICATIONS
(East Carolina University, 2019-06-07)Radiation exposure and associated radiation risks are major concerns for fetal development for pregnant patients in general, and in particular for overweight and obese pregnant patients who undergo diagnostic imaging or ... -
Four-Dimensional In Vivo Dosimetry By Dose Reconstruction Using Continuous Epid Images And Phase Sorting Method
(East Carolina University, 2015)In vivo dosimetry is widely used for patient specific dose evaluation and treatment verification in external beam radiation therapy (EBRT). There is a growing interest in using an electronic portal imaging device (EPID) ... -
Generation of Pseudo-CT using Two Sets of MRI Scans for MRI-only Radiation Therapy
(East Carolina University, 2019-07-16)WWith increasing interests in magnetic resonance imaging (MRI)-only radiation therapy (RT) and the emergence of MRI system integrated with the linear accelerator, a method substituting the computed tomography (CT) in ... -
Ion Traffic Across Cellular Membranes
(East Carolina University, 2010)The cell membrane protects the delicate internal machinery of the cell and hosts a complex transport system for ion exchange with the environment. Energy is continually expended to maintain a transmembrane electrical ... -
Mathematical Modeling of Oxygen Transport, Cell Killing and Cell Decision Making in Photodynamic Therapy of Cancer
(East Carolina University, 2012)In this study we present a model of in vitro cell killing through type II Photodynamic Therapy (PDT) for simulation of the molecular interactions leading to cell death in time domain in the presence of oxygen transport ... -
MODIFICATION OF CELL SURVIVAL RATES BY CERIUM OXIDE NANOPARTICLES FOR EXPOSURE TO PROTON RADIATION
(East Carolina University, 2017-05-03)Radiation therapy is a well-established and widely used treatment for a variety of malignancies in the human body. Current radiotherapy methods most frequently use x-rays to deliver a lethal dose to tumors with sufficient ... -
Optical and dielectric properties of metallic calcium, modeled generalized oscillator strength function of calcium, interaction cross sections of electrons, protons, and alpha particles with calcium
(East Carolina University, 2013)An analysis of the optical and the dielectric properties of calcium, determined from the literature, was performed. The optical functions of calcium were used for a calculation of the energy loss function of calcium. The ... -
Perturbation of Circadian Neuronal Oscillators with Low-Intensity Magnetic Stimulation
(East Carolina University, 2019-04-23)Circadian neuronal oscillatory dynamics are perturbed substantially in numerous neuropsychiatric diseases, such as Alzheimer's, Parkinson's, and depression. Moreover, desynchronization of neuronal oscillators complicates ... -
PROFILING EFFUSION CELLS BY QUANTITATIVE ANALYSIS OF MORPHOLOGY AND DIFFRACTION IMAGING PATTERNS
(East Carolina University, 2019-04-12)Profiling cells in human pleural and peritoneal effusion (PPE) samples is an essential task for cytological diagnosis of cancers and patient management. Conventional PPE cytology of a PPE sample is labor intensive and its ... -
A PROPOSED METHODOLOGY TO ASSESS HDR [superscript]192Ir RADIAL DOSE WITH FRICKE DOSIMETRY
(East Carolina University, 2011)The radial absorbed dose to water, D(r,theta), a quantity not yet directly measured with primary standards, was assessed with the Fricke solution which has been considered as an absolute aqueous solution to perform dosimetry. ...