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Review: Carbon Nanotubes and Chronic Granulomatous Disease
(2014-06-23)
Use of nanomaterials in manufactured consumer products is a rapidly expanding industry and potential toxicities are just beginning to be explored. Combustion-generated multiwall carbon nanotubes (MWCNT) or nanoparticles ...
Review of Musculoskeletal Injuries and Prevention in the Endoscopy Practitioner
(2014-08)
Practitioners of endoscopy often experience musculoskeletal pain and injury (most often in the back, neck, shoulders, hands, wrists, and thumbs) that are associated with the minute and repetitive strain that is placed on ...
Bouveret's Syndrome with Severe Esophagitis and a Purulent Fistula
(2014-04)
Bouveret's syndrome is a rare variant of gallstone ileus with an overall incidence of 1–3%. It is a rare cause of gastric outlet obstruction resulting from the passage and impaction of a large gallstone through a ...
Augmented coronary vascular smooth muscle response to endothelin-1 exacerbates cardiac injury following pulmonary exposure to engineered nanomaterials
(East Carolina University, 2014)
Multi-walled carbon nanotubes (MWCNT) and 60-carbon fullerenes (C60) are important engineered nanoparticles (ENP) used across industry. Exposure to ENP potentially promotes cardiovascular detriments. The hypotheses that ...
The induction of antigen-specific immunological tolerance and attenuation of inflammation via cytokine antigen fusion protein therapy in a mouse model of pulmonary inflammation
(East Carolina University, 2014)
Allergic asthma is a significant medical issue, affecting more than 300 million individuals and causing approximately 250,000 deaths each year. Current asthma therapies temporarily minimize discomfort and manage symptoms, ...
Relationship Between Cardiovascular Disease Risk and Fast Food Consumption in Undergraduate Honors College Students
(2014)
College students are often pushed towards fast foods as a means of getting a pleasurable, quick bite to eat. Fast foods are high in fat, salt, and sugar content and can lead to cardiovascular disease(CVD) risk. Honors ...
Circadian influences on myocardial infarction
(2014-10-30)
Components of circadian rhythm maintenance, or “clock genes,” are endogenous entrainable oscillations of about 24 h that regulate biological processes and are found in the suprachaismatic nucleus (SCN) and many peripheral ...
THE EFFECTS OF ACIDIC TUMOR MICROENVIRONMENT ON LYMPHOMA CELL RESPONSES TO CHEMOTHERAPEUTICS
(East Carolina University, 2014)
Acidic tumor microenvironment exists in many types of cancer. Altered glycolytic metabolism of tumor cells and deficient blood supply in tissues are major causes for this phenomenon. Lymphoma cells may have different ...
Prognostic factor from MR spectroscopy in rat with astrocytic tumour during radiation therapy
(2014-11-27)
Objective:
To investigate the relationship between the tumour volume and metabolic rates of astrocytic tumours using MR spectroscopy (MRS) during radiation therapy (RT).
Methods:
12 healthy male Sprague-Dawley® rats ...
Function and regulation of the polysaccharide utilization locus, don, in the gut symbiont bacteroides fragilis
(East Carolina University, 2014)
Bacteroides fragilis is the most common anaerobe isolated from clinical infections and in this report we demonstrate a novel feature of the species that is critical to their success as an opportunistic pathogen. Among the ...