Browsing by Author "Hu, Xin-Hua"
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Analysis of Polarized Diffraction Images of Human Red Blood Cells: A Numerical Study
Hu, Xin-Hua; Wang, Wenjin (2022-02-03) -
Comparison Study of Distinguishing Cancerous and Normal Prostate Epithelial Cells by Confocal and Polarization Diffraction Imaging
Lu, Jun Qing; Jiang, Wenhuan; Yang, Li V.; Ding, Junhua; Hu, Xin-Hua (2016-11-30) -
Development of a Diffraction Imaging Flow Cytometer for Study of Biological Cells
Jacobs, Kenneth M. (East Carolina University, 2010)Visible light interacts with biological cells primarily through elastic scattering. With coherent excitation the scattered light is coherent as well and contains much information about the cells morphology but with the ... -
DEVELOPMENT OF A NEW SPECTROPHOTOMETRIC METHOD FOR FULL CHARACTERIZATION OF TURBIDITY
Mutisya, Stephen M (East Carolina University, 2022-07-21)Characterization of turbid materials by determining their inherent optical properties have attracted strong research interest for potentially wide applications in fields such as material analysis and biomedical optics. The ... -
Feasibility Study of Dual Energy Radiographic Imaging for Target Localization in Radiotherapy for Lung Tumors
Huo, Jie; Zhu, Xianfeng; Dong, Yang; Yuan, Zhiyong; Wang, Ping; Wang, Xuemin; Wang, Gang; Hu, Xin-Hua; Feng, Yuanming (2014)Purpose Dual-energy (DE) radiographic imaging improves tissue discrimination by separating soft from hard tissues in the acquired images. This study was to establish a mathematic model of DE imaging based on intrinsic ... -
In vivo imaging and modeling of artery blood pressure wave and interaction with light in time domain
Jin, Jiahong (East Carolina University, 2021-11-29)Artery blood flow driven by pressure wave is essential for human life. The long-term research goal is to establish a foundation for future translation of the imaging photoplethysmography (iPPG) method into applications ... -
Label-free classification of cultured cells through diffraction imaging
Dong, Ke; Feng, Yuanming; Jacobs, Kenneth M.; Lu, Jun Q.; Brock, R. Scott; Yang, Li V.; Bertrand, Fred E.; Farwell, Mary A.; Hu, Xin-Hua (2011-05)Automated classification of biological cells according to their 3D morphology is highly desired in a flow cytometer setting. We have investigated this possibility experimentally and numerically using a diffraction imaging ... -
Mathematical Modeling of Oxygen Transport, Cell Killing and Cell Decision Making in Photodynamic Therapy of Cancer
Gkigkitzis, Ioannis (East Carolina University, 2012)In this study we present a model of in vitro cell killing through type II Photodynamic Therapy (PDT) for simulation of the molecular interactions leading to cell death in time domain in the presence of oxygen transport ... -
A new assessment model for tumor heterogeneity analysis with [18]F-FDG PET images
Wang, Ping; Xu, Wengui; Sun, Jian; Yang, Chengwen; Wang, Gang; Sa, Yu; Hu, Xin-Hua; Feng, Yuanming (2016-01)It has been shown that the intratumor heterogeneity can be characterized with quantitative analysis of the [18]F-FDG PET image data. The existing models employ multiple parameters for feature extraction which makes it ... -
Photoplethysmographic imaging and analysis of pulsatile pressure wave in palmar artery at 10 wavelengths
Jin, Jiahong; Lu, Jun Qing; Chen, Cheng; Zhou, Ruihai; Hu, Xin-Hua (2022-11-10)Significance As a noncontact method, imaging photoplethysmography (iPPG) may provide a powerful tool to measure pulsatile pressure wave (PPW) in superficial arteries and extract biomarkers for monitoring of artery wall ... -
PROFILING EFFUSION CELLS BY QUANTITATIVE ANALYSIS OF MORPHOLOGY AND DIFFRACTION IMAGING PATTERNS
Al-Qaysi, Safaa (East Carolina University, 2019-04-12)Profiling cells in human pleural and peritoneal effusion (PPE) samples is an essential task for cytological diagnosis of cancers and patient management. Conventional PPE cytology of a PPE sample is labor intensive and its ... -
Quantitative Analysis and Comparison of 3D Morphology Between Viable and Apoptotic MCF-7 Breast Cancer Cells and Characterization of Nuclear Fragmentation
Lu, Jun Qing; Chen, Zhan; Ables, Elizabeth Tweedie; Scemama, Jean-Luc; Yang, Li V.; Hu, Xin-Hua (2017-09-08) -
Quantitative analysis and comparison of 3D morphology between viable and apoptotic MCF-7 breast cancer cells and characterization of nuclear fragmentation
Wen, Yuhua; Chen, Zhan; Lu, Jianfen; Ables, Elizabeth Tweedie; Scemama, Jean-Luc; Yang, Li V.; Lu, Jun Q.; Hu, Xin-Hua (2017-09-08)Morphological changes in apoptotic cells provide essential markers for defining and detec- tion of apoptosis as a fundamental mechanism of cell death. Among these changes, the nuclear fragmentation and condensation have ... -
Quantitative analysis and comparison of 3D morphology between viable and apoptotic MCF-7 breast cancer cells and characterization of nuclear fragmentation
Wen, Yuhua; Chen, Zhan; Lu, Jianfen; Ables, Elizabeth Tweedie; Scemama, Jean-Luc; Yang, Liv. V.; Lu, Jun Q.; Hu, Xin-Hua (2017-09-08)Morphological changes in apoptotic cells provide essential markers for defining and detection of apoptosis as a fundamental mechanism of cell death. Among these changes, the nuclear fragmentation and condensation have ... -
Quantitative Assessment of Image Motion Blur in Diffraction Images of Moving Biological Cells
Hu, Xin-Hua (2016-02) -
Quantitative assessment of image motion blur in diffraction images of moving biological cells
Wang, He; Jin, Changrong; Feng, Yuanming; Qi, Dandan; Sa, Yu; Hu, Xin-Hua (2016-02)Motion blur (MB) presents a significant challenge for obtaining high-contrast image data from biological cells with a polarization diffraction imaging flow cytometry (p-DIFC) method. A new p-DIFC experimental system has ... -
Quantitative Characterization of Turbidity by Radiative Transfer Based Reflectance Imaging
Hu, Xin-Hua (2018-04-04) -
Real Activities Manipulation by Bidders Prior to Mergers and Acquisitions
Hu, Xin-Hua (2017-08-14) -
Resolving power of diffraction imaging with an objective: a numerical study
Wang, Wenjin; Liu, Jing; Lu, Jun Q.; Ding, Junhua; Hu, Xin-Hua (2017-05)Diffraction imaging in the far-field can detect 3D morphological features of an object for its coherent nature. We describe methods for accurate calculation and analysis of diffraction images of scatterers of single and ...