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Now showing items 1547-1566 of 10631
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Characterization of Two Novel Mutants of DNA Polymerase Delta in Drosophila melanogaster
(East Carolina University, 2011)DNA is the genetic material for all living organisms which is constantly being unpackaged, replicated and repackaged. The replication of this genetic material involves numerous different proteins; however, DNA polymerase ... -
Characterization of Vestibular Dysfunction in the Mouse Model for Usher Syndrome 1F
(East Carolina University, 2005-06)The deaf-circling Ames waltzer (av) mouse harbors a mutation in the protocadherin 15 (Pcdh15) gene and is a model for inner ear defects associated with Usher syndrome type 1F. Earlier studies showed altered cochlear hair ... -
Characterization of Wet-Heat Inactivation of Single Spores of Bacillus Species by Dual-Trap Raman Spectroscopy and Elastic Light Scattering
(2010-03)Dual-trap laser tweezers Raman spectroscopy (LTRS) and elastic light scattering (ELS) were used to investigate dynamic processes during high-temperature treatment of individual spores of Bacillus cereus, Bacillus megaterium, ... -
Characterizations of Cross-Bridges in the Presence of Saturating Concentrations of MgAMP-PNP in Rabbit Permeabilized Psoas Muscle
(1998-06)Several earlier studies have led to different conclusions about the complex of myosin with MgAMP-PNP. It has been suggested that subfragment 1 of myosin (S1)-MgAMP-PNP forms an S1-MgADP-like state, an intermediate between ... -
Characterizing Angling Trends among Blue Marlin Anglers Following the 2008 Circle Hook Regulation
(East Carolina University, 2022-05-06)The blue marlin Makaira nigricans (Lacepède, 1802) is a highly migratory, large pelagic predator that is subject to overfishing as bycatch in longline fisheries and as game fish in recreational tournaments, such as the ... -
Characterizing Coastal Subenvironments with Modern Foraminiferal Assemblages: Bear Island and Bogue Banks, North Carolina
(East Carolina University, 2018-08-30)North Carolina's coastline consists of an extensive barrier island system, with inlets acting as pathways for the exchange of sediment and water from estuarine and open ocean environments. Reconstructing past coastal changes ... -
Characterizing Environmental and Physicochemical Conditions in Nursery Areas of River Herring in Chowan River, North Carolina
(East Carolina University, 2012)Anadromous fishes such as blueback herring Alosa aestivalis and alewife A. pseudoharengus, utilize sounds, rivers, and tributaries during spawning. Collectively known as river herring, these two ecologically important ... -
Characterizing Interactions of Thioflavin-T with Native Proteins Especially Bovine Serum Albumin
(East Carolina University, 2017-05-03)Thioflavin T is a fluorescent probe used to monitor formation of cross [beta]-sheet rich amyloid fibrils. Involvement of the amyloid fibrils is implicated in more than 50 human diseases, such as Alzheimer's, Parkinson's ... -
Characterizing Multigenerational Effects of Nicotine-Dependent Behaviors in Caenorhabditis Elegans
(East Carolina University, 2017-05-03)This project aims to investigate the effects nicotine, a highly addictive chemical associated with tobacco smoking, have on offspring (F1 and F2) using the model organism Caenorhabditis elegans (C. elegans). C. elegans is ... -
Characterizing Patterns And Drivers Of Land Use/Land Cover Change Along The Atlantic Coast Barrier Beaches : Examining The Roles Of Development Pressure, Spatial Accessibility, And Policy
(East Carolina University, 2013)Within the context of land change science coastal areas are often overlooked. Coastal areas around the world and within the U.S. represent the largest concentrations of people, development, and wealth. Natural, social, ... -
Characterizing the Binding of Ca2+ and Cd2+ to EF-hand Peptide V of Calbindin D28K and EF-hand Peptides III and IV of Human Cardiac Troponin C Using CD, ITC, and Fluorescence Spectroscopy
(East Carolina University, 8/5/2020)Calcium-binding EF-hand proteins are ubiquitous in the cell and are essential for many biological functions such as muscle contraction and cell signaling. Divalent cadmium, Cd²⁺, and lead, Pb²⁺ are toxic metal ions that ... -
Characterizing the Binding of Toxic and Essential Metals to EF-Hand Peptides III and IV of Human Cardiac Troponin C Using Fluorescence Spectroscopy and Isothermal Titration Calorimetry
(East Carolina University, 2023-12-05)Cadmium is one of the most toxic natural and anthropogenic metals found in our environment. Exposure to cadmium is associated with several cardiovascular conditions, neurodegenerative disorders, and cancers. Cadmium’s ... -
Characterizing the Deceased Mariners of the Swedish Warship Vasa : An Analysis of Personal Possessions Found in Association with Human Remains
(East Carolina University, 2014)On August 10, 1628, as onlookers watched in dismay, the newest and most powerful warship in Northern Europe, a symbol of the prestige and power of Sweden and Sweden's King Gustav II Adolf, heeled over and sank in Stockholm ... -
Characterizing the Expression Pattern of miR167-Regulated ZmArf3 and ZmArf30 in Maize Inflorescences
(East Carolina University, 2014)Plant growth and development depends on the activity of meristems, pools of stem cells that generate leaves and other organs. Maize (corn) produces two inflorescences, the tassel and ear, which are patterned by a series ... -
Characterizing the geographic variability of opioid mortality in North Carolina, 2014-2016
(East Carolina University, 2019-12-10)The opioid crisis has proven to be one of the most devastating drug epidemics experienced in the United States. While many studies have associated the rise in opioid mortality rates to overprescribing of opioid painkillers, ... -
Characterizing the Role of Pectin in Cell Wall Composition and Organ Initiation in Maize
(East Carolina University, 2022-12-07)Plants are constantly developing new organs throughout their life and these organs arise from stem cell pools called meristems. Organ primordia are generated on the flanks of meristems when stem cells differentiate into ... -
Characterizing the role of the Early Gene at 23 (E23) in Drosophila Melanogaster Oogenesis
(East Carolina University, 2016-04-29)Drosophila melanogaster (fruit fly) females undergo oogenesis to create oocytes from undifferentiated stem cells in the ovary. Similar to estrogen in humans, the steroid hormone ecdysone in fruit flies has a known role in ...