Browsing by Issue Date
Now showing items 161-180 of 10629
-
Epigenetic mechanisms of drug resistance: drug-induced DNA hypermethylation and drug resistance.
(East Carolina University, 1993-04-01)In a model system employing Chinese hamster V-79 cells, the DNA synthesis inhibitor 3'-azido-3'- deoxythymidine (BW A509U, AZT) was shown to induce genome-wide DNA hypermethylation, low-frequency silencing of thymidine ... -
Genetic and biochemical analysis of a novel Ambler class A β-Lactamase responsible for cefoxitin resistance in Bacteroides species.
(East Carolina University, 1993-05)A clinical isolate of Bacteroides vulgatus was resistant to tetracycline, clindamycin, ampicillin, cephaloridine, cefoxitin, and other 13-lactam antibiotics except imipenem. 13-Lactam resistance was mediated by a ... -
Abundance and Viability of Striped Bass Eggs Spawned in the Roanoke River, North Carolina in 1991
(East Carolina University, 1993-05)Striped bass spawning activity in the Roanoke River, North Carolina, was documented in 1991 by sampling for eggs at Barnhill’s Landing (River Mile 117), which is just downstream of the spawning grounds between the towns ... -
Identification of a circular intermediate in the transfer and transposition of Tn4555, a mobilizable transposon from Bacteroides spp.
(East Carolina University, 1993-05)Transmissible cefoxitin (FX) resistance in Bacteroides vulgatus CLA341 was associated with the 12.5-kb, mobilizable transposon, Tn4555, which encoded the 13-lactamase gene cfxA. Transfer occurred by a conjugation-like ... -
Autocrine production of extracellular catalase prevents apoptosis of the human CEM T-cell line in serum-free medium.
(East Carolina University, 1993-05-15)CCRF-CEM is a human T-cell line originally isolated from a child with acute lymphoblastic leukemia. At cell densities > 2 x 10 cells per ml, CEM cells grow in serum-free medium, but at lower cell densities the cultures ... -
Purification and Partial Characterization of Relaxin and Relaxin Precursors from the Hamster Placenta
(East Carolina University, 1993-07)Previous immunological studies have indicated that the molecular structure of hamster relaxin is quite different from that of porcine relaxin. In the present study, hamster relaxin was purified from placentas and ... -
Enzymatic determination of itoic acid, a Bacillus subtilis siderophore, and 2,3-dihydroxybenzoic acid.
(East Carolina University, 1993-07)A specific enzymatic method to determine the amounts of itoic acid, a Bacillus subtilis siderophore, and 2,3-dihydroxybenzoic acid (2,3-DHBA) was devised. A sample was incubated first with hippurate hydrolase andthenwith ... -
Neurogenic inflammation and sensitivity to environmental chemicals.
(East Carolina University, 1993-08)Neurogenic inflammation as a pathway distinct from antigen-driven, immune-mediated inflammation may play a pivotal role in understanding a broad class of environmental health problems resulting from chemical exposures. ... -
Characterization of a caldesmon fragment that competes with myosin-ATP binding to actin.
(East Carolina University, 1993-08)The protein caldesmon inhibits actin-activated ATP hydrolysis of myosin and inhibits the binding of myosin*ATP to actin. Afragment isolated from a chymotryptic digest of caldesmon contains features of the intact molecule ... -
Prenatal diagnosis of a giant intracranial teratoma associated with pulmonary hypoplasia.
(East Carolina University, 1993-10)We present a case in which an intracranial tumour replacing all intracranial contents was diagnosed by sonography at 31 weeks' gestation. The patient was delivered by caesarean section and died shortly after delivery. At ... -
Benthic Biocriteria Assessment of the Lower Roanoke River, North Carolina: A Final Report to Weyerhaeuser Paper Company
(East Carolina University, 1993-10)Recent changes in environmental monitoring procedures of industrial activities suggest that future environmental assessments will be made using biocriteria methodology. Benthic macroinvertebrates have been the most often ... -
Roanoke River Water Flow Committee Report for 1991-1993
(East Carolina University, 1993-11)A Committee of representatives from State and Federal agencies and State universities was formed in 1988 to gather information on natural resources of the lower Roanoke River watershed in North Carolina and to recommend a ... -
Cloning and characterization of the endogenous cephalosporinase gene, cepA, from Bacteroides fragilis reveals a new subgroup of Ambler class A beta-lactamases.
(East Carolina University, 1993-11)Bacteroides frgiglis CS30 is a clinical isolate resistant to high concentrations of benzylpenicillin and cephaloridine but not to cephamycin or penem antibiotics. beta-Lactam resistance is mediated by a chromosomally encoded ... -
Cohomology classes associated to anomalies
(1993-12)One of the proposed settings for the description of anomalies in the setting of gauge field theories is a local bicomplex associated to a principal fiber bundle $ G \to P \to M$. It is a bigraded algebra with two differentials ... -
Stereotypes of Stutterers and Nonstutterers in Three Rural Communities in Newfoundland
(East Carolina University, 1993-12)The existence of a negative stereotype of stutterers among residents of three Small, rural communities in Newfoundland, Canada was investigated. Members of these communities (n=106) completed a 25 item semantic differential ... -
Cardiac tamponade and pericardial disorders in connective tissue diseases: case report and literature review.
(East Carolina University, 1994-02)Pericardial disorders occurring in connective tissue diseases are not uncommon and may present as acute or chronic pericarditis with or without an effusion. In many instances, a diagnosis of pericardial involvement is not ...