Browsing by Author "Dohm, G. Lynis"
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Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4.
Friedman, Jacob E.; Dohm, G. Lynis; Leggett-Frazier, Nancy; Elton, Charles W.; Tapscott, Edward B.; Pories, Walter J.; Caro, Jose F. (East Carolina University, 1992-02)A major defect contributing to impaired insulin action in human obesity is reduced glucose transport activity in skeletal muscle. This study was designed to determine whether the improvement in whole body glucose disposal ... -
Some effects of endurance training on protein metabolism
Puente, Fernando Ren{acute}e. -
Stimulation of glucose uptake by insulin-like growth factor II in human muscle is not mediated by the insulin-like growth factor II/mannose 6-phosphate receptor.
Burguera, Bartolome; Elton, Charles W.; Tapscott, Edward B.; Pories, Walter J.; Dimarchi, Richard; Sakano, Katsu-ichi; Dohm, G. Lynis (East Carolina University, 1994-06-15)Although the growth-promoting effects of insulin-like growth factor II (IGF-II) have been intensively studied, the acute actions of this hormone on glucose metabolism have been less well evaluated, especially in skeletal ... -
The effects of exercise on protein degradation
Williams, Richard T. -
The role of CaMK in the activity dependent regulation of GLUT4 gene expression
Jensen, Ellis Benjamin -
Time course metabolome of Roux-en-Y gastric bypass confirms correlation between leptin, body weight and the microbiome
Seridi, Loqmane; Leo, Gregory C.; Dohm, G. Lynis; Pories, Walter J.; Lenhard, James (2018-05-31)Roux-en-Y gastric bypass (RYGB) is an effective way to lose weight and reverse type 2 dia- betes. We profiled the metabolome of 18 obese patients (nine euglycemic and nine diabet- ics) that underwent RYGB surgery and seven ... -
Transcriptional regulation of muscle fatty acid-binding protein.
Carey, Julie O.; Neufer, P. Darrell; Farrar, Roger P.; Veerkamp, Jacques H.; Dohm, G. Lynis (East Carolina University, 1994-03-15)Heart fatty acid-binding protein (H-FABP) is present in a wide variety of tissues but is found in the highest concentration in cardiac and red skeletal muscle. It has been proposed that the expression of H-FABP correlates ... -
Type 2 Diabetes Modifies Skeletal Muscle Gene Expression Response to Gastric Bypass Surgery
Dohm, G. Lynis; Barberio, Matthew D.; Pories, Walter J.; Gadaleta, Natalie A.; Houmard, Joseph A.; Nadler, Evan P.; Hubal, Monica J. (2021-10-06) -
Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus.
Pories, Walter J.; Swanson, Melvin S.; MacDonald, Kenneth G. Jr.; Long, Stuart B.; Morris, Patricia G.; Brown, Brenda M.; Barakat, Hisham A.; deRamon, Richard A.; Israel, R. Gay; Dolezal, Jeanette M.; Dohm, G. Lynis (East Carolina University, 1995-09)OBJECTIVE: This report documents that the gastric bypass operation provides long-term control for obesity and diabetes. SUMMARY BACKGROUND DATA: Obesity and diabetes, both notoriously resistant to medical therapy, continue ...