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Now showing items 5263-5282 of 10630
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Installation of Metal-Binding Functionality at Lysine Residues via Azide-Alkyne "Click Chemistry"
(2015-04-29)A novel non-natural amino acid designed to bind divalent metal ions, dubbed Lys(PYRIT), was prepared in a “click reaction” by treating Fmoc-Lys(N3)-OH with 2-ethynylpyridine and Cu(I). It was incorporated into a 12-residue ... -
Instituting Change in Blood Clot Prophylaxis Protocol for Perioperative Patients
(2022-04-22)Perioperative blood clots are a common, preventable occurrence in the healthcare setting. Patients undergoing surgery are at high risk for developing a deep venous thrombosis (DVT) or pulmonary embolus (PE) for a variety ... -
Institutional Betrayal: Students' Experiences with Formally Reporting a College Sexual Assault
(East Carolina University, 2020-11-06)Nearly one in five U.S. college women will experience a sexual assault while enrolled in college (Cantor et al., 2015; Jordan et al., 2014; Muehlenhard et al., 2017; Zinzow et al., 2010). Following a sexual assault, many ... -
Institutional Ownership Stability and Dividend Payout Policy
(2017-10-09) -
INSTRUCTIONAL LEADERSHIP AND PROFESSIONAL LEARNING IN A RURAL NORTH CAROLINA SCHOOL DISTRICT
(East Carolina University, 2014)This case study examined the instructional leadership of principals as co-participants in professional learning with teachers in a rural school district in eastern North Carolina. Teacher and principal interviews were the ... -
Instructions for Uploading to The ScholarShip
(2021-04-21)This is simply to help students with uploading to The ScholarShip. -
INSULATION IN RESIDENTIAL HOME BUILDINGS: COST COMPARISON OF TRADITIONAL AND HEMP BUILDING INSULATION
(East Carolina University, 2022-05-04)The materials from harvested from hemp plants have become an increasingly popular material for building across the world based on its availability and sustainable properties. Hemp is being used as an alternative insulation ... -
Insulin in the nervous system and the mind: Functions in metabolism, memory, and mood
(2016)Background: Insulin, a pleotrophic hormone, has diverse effects in the body. Recent work has highlighted the important role of insulin's action in the nervous system on glucose and energy homeostasis, memory, and mood. ... -
Insulin responsiveness in skeletal muscle is determined by glucose transporter (Glut4) protein level.
(East Carolina University, 1990-09-01)Glucose transport in skeletal muscle is mediated by two distinct transporter isoforms, designated muscle/adipose glucose transporter (Glut4) and erythrocyte/HepG2/brain glucose transporter (Glutl), which differ in both ... -
Insulin Stimulated Lactate Production
(2014)It has been shown that Type 2 diabetic patients who undergo Roux-en-Y Gastric Bypass surgery (RYGB) show a decrease in muscle lactate production, liver glucose production and pancreatic insulin secretion. To explain these ... -
Insulin-like growth factor I binding in hepatocytes from human liver, human hepatoma, and normal, regenerating, and fetal rat liver.
(East Carolina University, 1988-04)Insulin-like growth factor-I (IGF-I) in human hepatoma cells (HEP-G2) has, in addition to its effect on cell growth, shortterm metabolic effects acting through its own receptor. We have demonstrated that normal ... -
Insulin/IGF1-PI3K-dependent nucleolar localization of a glycolytic enzyme – phosphoglycerate mutase 2, is necessary for proper structure of nucleolus and RNA synthesis
(2015-07)Phosphoglycerate mutase (PGAM), a conserved, glycolytic enzyme has been found in nucleoli of cancer cells. Here, we present evidence that accumulation of PGAM in the nucleolus is a universal phenomenon concerning not only ... -
Insulin/IGF1-PI3K-dependent nucleolar localization of a glycolytic enzyme – phosphoglycerate mutase 2, is necessary for proper structure of nucleolus and RNA synthesis
(2015)Phosphoglycerate mutase (PGAM), a conserved, glycolytic enzyme has been found in nucleoli of cancer cells. Here, we present evidence that accumulation of PGAM in the nucleolus is a universal phenomenon concerning not ...