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Now showing items 6649-6668 of 10631
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A Novel Educational Intervention: Improving Abdominal Pressure Strategies during Colonoscopy
(2021-07-23)Gastroenterology (endoscopy) procedures continue to increase in volume as innovative therapeutic endoscopy procedures are performed to meet the increasing demand for minimally invasive procedures. During endoscopy procedures, ... -
Novel Function of PUF Proteins and Their Partners in Spermatogenesis and Spermatocyte-Derived Germline Tumors in Caenorhabditis elegans
(East Carolina University, 2022-04-27)Conserved PUF (Pumilio and FBF) proteins repress the translation by binding to its target mRNA 3' untranslated region (3'UTR). C. elegans has 11 PUF proteins. Among them, we focused on two FBFs (FBF-1 and FBF-2) and PUF-8. ... -
NOVEL MECHANISMS GOVERNING SKELETAL MUSCLE MITOCHONDRIAL BIOENERGETICS : OXPHOS EFFICIENCY AND cAMP/PKA SIGNALING
(East Carolina University, 2014)Understanding the regulation of cellular metabolism is paramount to treating the growing prevalence of metabolic disease worldwide. In cellular metabolism, mitochondrial oxidative phosphorylation (OXPHOS) plays a key role ... -
Novel Nano-Based Antibacterial Therapeutic Against Hospital Acquired Infection
(East Carolina University, 2022-07-19)Rising nosocomial infections, also called hospital-acquired infections (HAIs), are of imminent public health concern as common antibiotics, such as ampicillin and kanamycin, are becoming less effective against bacterial ... -
Novel Nano-Based Antibacterial Therapeutic Against Hospital Acquired Infection
(East Carolina University, 2022-07-19)Rising nosocomial infections, also called hospital-acquired infections (HAIs), are of imminent public health concern as common antibiotics, such as ampicillin and kanamycin, are becoming less effective against bacterial ... -
NOVEL NUCLEOLAR LOCALIZATION OF SYNAPTOPODIN-2 ISOFORM IN PROLIFERATING HT-29 CELLS
(East Carolina University, 2021-07-13)Members of the Synaptopodin family regulate [alpha]-actinin and actin-bundling activity, in an isoform specific manner (Asunama et al., 2005). The ability to affect actin polymerization and bundling highlights the critical ... -
A novel particle filtering method for estimation of pulse pressure variation during spontaneous breathing
(2016-08-11)Background: We describe the first automatic algorithm designed to estimate the pulse pressure variation (PPVPPV) from arterial blood pressure (ABP) signals under spontaneous breathing conditions. While currently there are ... -
Novel Pelagic Iron-Oxidizing Zetaproteobacteria from the Chesapeake Bay Oxic–Anoxic Transition Zone
(2017-07-18)Chemolithotrophic iron-oxidizing bacteria (FeOB) could theoretically inhabit any environment where Fe(II) and O2 (or nitrate) coexist. Until recently, marine Fe-oxidizing Zetaproteobacteria had primarily been observed in ... -
Novel role for thioredoxin reductase-2 in mitochondrial redox adaptations to obesogenic diet and exercise in heart and skeletal muscle
(2013)Increased fatty acid availability and oxidative stress are physiological consequences of exercise (Ex) and a high-fat, high-sugar (HFHS) diet. Despite these similarities, the global effects of Ex are beneficial, whereas ... -
NOVEL ROLE OF HUMAN T-CELL LEUKEMIA VIRUS TYPE-1 ENCODED PROTEIN HBZ IN VIRAL TRANSMISSION THROUGH CELL-TO-CELL CONTACT
(East Carolina University, 2017-04-28)The complex retrovirus Human T cell leukemia virus type I (HTLV-1) is the etiologic agent of several diseases, including Adult T cell leukemia (ATL), a fatal hematological malignancy that affects mainly CD4+ T-cells. Freshly ... -
Novel roles for ecdysone receptor in the Drosophila germline
(East Carolina University, 2022-07-01)Oogenesis, the process by which a viable egg is produced, demands carefully coordinated communication between somatic and germ cell populations, relying on both local and systemic factors such as steroid hormones for ... -
Novel roles for ecdysone receptor in the Drosophila germline
(East Carolina University, 2022-07-01)Oogenesis, the process by which a viable egg is produced, demands carefully coordinated communication between somatic and germ cell populations, relying on both local and systemic factors such as steroid hormones for ... -
A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women
(2017-03-02)SNP rs7903146 in the Wnt pathway’s TCF7L2 gene is the variant most significantly associ- ated with type 2 diabetes to date, with associations observed across diverse populations. We sought to determine whether variants in ... -
A Novel Wide Area Multiple Azimuth Beam ISAR Imaging System
(2019-04-30) -
NOVELTY DETECTION FOR PREDICTIVE MAINTENANCE
(East Carolina University, 8/5/2020)Since the advent of Industry 4. 0 significant research has been conducted to apply machine learning to the vast array of Internet of Things (IoT) data produced by Industrial Machines. One such topic is to Predictive ... -
Novice Teachers’ Preparedness Towards Successfully Interacting with Culturally Diverse Student Populations
(East Carolina University, 2019-07-15)Teacher effectiveness is the most influential factor to student achievement. Systems of public education in the United States have traditionally centered on White, middle class norms, as suggested by the founding arguments ...